Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals following mRNA vaccination

Novel mRNA vaccines for SARS-CoV-2 have been authorized for emergency use. Despite their efficacy in clinical trials, data on mRNA vaccine-induced immune responses are mostly limited to serological analyses. Here, we interrogated antibody and antigen-specific memory B cells over time in 33 SARS-CoV-...

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Detalles Bibliográficos
Autores principales: Goel, Rishi R., Apostolidis, Sokratis A., Painter, Mark M., Mathew, Divij, Pattekar, Ajinkya, Kuthuru, Oliva, Gouma, Sigrid, Hicks, Philip, Meng, Wenzhao, Rosenfeld, Aaron M., Dysinger, Sarah, Lundgreen, Kendall A., Kuri-Cervantes, Leticia, Adamski, Sharon, Hicks, Amanda, Korte, Scott, Oldridge, Derek A., Baxter, Amy E., Giles, Josephine R., Weirick, Madison E., McAllister, Christopher M., Dougherty, Jeanette, Long, Sherea, D’Andrea, Kurt, Hamilton, Jacob T., Betts, Michael R., Luning Prak, Eline T., Bates, Paul, Hensley, Scott E., Greenplate, Allison R., Wherry, E. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8158969/
https://www.ncbi.nlm.nih.gov/pubmed/33858945
http://dx.doi.org/10.1126/sciimmunol.abi6950

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