Transcription Factor β-Catenin Plays a Key Role in Fluid Flow Shear Stress-Mediated Glomerular Injury in Solitary Kidney

Increased fluid flow shear stress (FFSS) in solitary kidney alters podocyte function in vivo. FFSS-treated cultured podocytes show upregulated AKT-GSK3β-β-catenin signaling. The present study was undertaken to confirm (i) the activation of β-catenin signaling in podocytes in vivo using unilaterally...

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Detalles Bibliográficos
Autores principales: Srivastava, Tarak, Heruth, Daniel P., Duncan, R. Scott, Rezaiekhaligh, Mohammad H., Garola, Robert E., Priya, Lakshmi, Zhou, Jianping, Boinpelly, Varun C., Novak, Jan, Ali, Mohammed Farhan, Joshi, Trupti, Alon, Uri S., Jiang, Yuexu, McCarthy, Ellen T., Savin, Virginia J., Sharma, Ram, Johnson, Mark L., Sharma, Mukut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159099/
https://www.ncbi.nlm.nih.gov/pubmed/34069476
http://dx.doi.org/10.3390/cells10051253

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