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Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals
Objective: To evaluate the odds of association between suicidal ideation and/or attempt with comorbid eating disorders in adolescents with major depressive disorder (MDD). Methods: We conducted a cross-sectional study and included 122,020 adolescents with a primary diagnosis of MDD from the nationwi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159103/ https://www.ncbi.nlm.nih.gov/pubmed/34069446 http://dx.doi.org/10.3390/bs11050078 |
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author | Patel, Rikinkumar S. Machado, Tanya Tankersley, William E. |
author_facet | Patel, Rikinkumar S. Machado, Tanya Tankersley, William E. |
author_sort | Patel, Rikinkumar S. |
collection | PubMed |
description | Objective: To evaluate the odds of association between suicidal ideation and/or attempt with comorbid eating disorders in adolescents with major depressive disorder (MDD). Methods: We conducted a cross-sectional study and included 122,020 adolescents with a primary diagnosis of MDD from the nationwide inpatient sample (NIS, 2012–2014). They were sub-grouped by a comorbid diagnosis of eating disorders (N = 1675). We calculated the adjusted odds ratio (aOR) using a logistic regression model with demographic confounders for associations of eating disorders with suicidal ideation and attempt. Results: Suicidal ideations were seen in a higher proportion of adolescents with eating disorders (46.3% vs. 14.2% in those without eating disorders). On the contrary, a low proportion of adolescents with eating disorders had suicidal attempts (0.9% vs. 39.4% in those without eating disorders). Overall, eating disorders were associated with higher odds for suicidal ideations (aOR 5.36, 95% CI 4.82–5.97) compared to those without eating disorders, but with lower odds of suicidal attempt (aOR 0.02, 95% CI 0.01–0.03). Conclusions: Adolescents with MDD and comorbid eating disorders had five-times increased odds of suicidal ideations but lower odds of a suicide attempt. Self-harm/injurious behaviors are early signs of suicidal ideations in these patients. A collaborative care model is required for the screening, early diagnosis, and management of adolescents with eating disorders to improve their quality of life. |
format | Online Article Text |
id | pubmed-8159103 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81591032021-05-28 Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals Patel, Rikinkumar S. Machado, Tanya Tankersley, William E. Behav Sci (Basel) Article Objective: To evaluate the odds of association between suicidal ideation and/or attempt with comorbid eating disorders in adolescents with major depressive disorder (MDD). Methods: We conducted a cross-sectional study and included 122,020 adolescents with a primary diagnosis of MDD from the nationwide inpatient sample (NIS, 2012–2014). They were sub-grouped by a comorbid diagnosis of eating disorders (N = 1675). We calculated the adjusted odds ratio (aOR) using a logistic regression model with demographic confounders for associations of eating disorders with suicidal ideation and attempt. Results: Suicidal ideations were seen in a higher proportion of adolescents with eating disorders (46.3% vs. 14.2% in those without eating disorders). On the contrary, a low proportion of adolescents with eating disorders had suicidal attempts (0.9% vs. 39.4% in those without eating disorders). Overall, eating disorders were associated with higher odds for suicidal ideations (aOR 5.36, 95% CI 4.82–5.97) compared to those without eating disorders, but with lower odds of suicidal attempt (aOR 0.02, 95% CI 0.01–0.03). Conclusions: Adolescents with MDD and comorbid eating disorders had five-times increased odds of suicidal ideations but lower odds of a suicide attempt. Self-harm/injurious behaviors are early signs of suicidal ideations in these patients. A collaborative care model is required for the screening, early diagnosis, and management of adolescents with eating disorders to improve their quality of life. MDPI 2021-05-19 /pmc/articles/PMC8159103/ /pubmed/34069446 http://dx.doi.org/10.3390/bs11050078 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Patel, Rikinkumar S. Machado, Tanya Tankersley, William E. Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals |
title | Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals |
title_full | Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals |
title_fullStr | Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals |
title_full_unstemmed | Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals |
title_short | Eating Disorders and Suicidal Behaviors in Adolescents with Major Depression: Insights from the US Hospitals |
title_sort | eating disorders and suicidal behaviors in adolescents with major depression: insights from the us hospitals |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159103/ https://www.ncbi.nlm.nih.gov/pubmed/34069446 http://dx.doi.org/10.3390/bs11050078 |
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