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Asymmetric synthesis of primary amines catalyzed by thermotolerant fungal reductive aminases

Chiral primary amines are important intermediates in the synthesis of pharmaceutical compounds. Fungal reductive aminases (RedAms) are NADPH-dependent dehydrogenases that catalyse reductive amination of a range of ketones with short-chain primary amines supplied in an equimolar ratio to give corresp...

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Detalles Bibliográficos
Autores principales:	Mangas-Sanchez, Juan, Sharma, Mahima, Cosgrove, Sebastian C., Ramsden, Jeremy I., Marshall, James R., Thorpe, Thomas W., Palmer, Ryan B., Grogan, Gideon, Turner, Nicholas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159254/ https://www.ncbi.nlm.nih.gov/pubmed/34122962 http://dx.doi.org/10.1039/d0sc02253e

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