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Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics

With growing understanding of the underlying pathways of polyketide biosynthesis, along with the continual expansion of the synthetic biology toolkit, it is becoming possible to rationally engineer and fine-tune the polyketide biosynthetic machinery for production of new compounds with improved prop...

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Detalles Bibliográficos
Autores principales: Wang, Luoyi, Song, Zhongshu, Race, Paul R., Spencer, James, Simpson, Thomas J., Crump, Matthew P., Willis, Christine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159325/
https://www.ncbi.nlm.nih.gov/pubmed/34122978
http://dx.doi.org/10.1039/c9sc06192d