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Mixing and matching genes of marine and terrestrial origin in the biosynthesis of the mupirocin antibiotics
With growing understanding of the underlying pathways of polyketide biosynthesis, along with the continual expansion of the synthetic biology toolkit, it is becoming possible to rationally engineer and fine-tune the polyketide biosynthetic machinery for production of new compounds with improved prop...
Autores principales: | Wang, Luoyi, Song, Zhongshu, Race, Paul R., Spencer, James, Simpson, Thomas J., Crump, Matthew P., Willis, Christine L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159325/ https://www.ncbi.nlm.nih.gov/pubmed/34122978 http://dx.doi.org/10.1039/c9sc06192d |
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