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Hair-Dye-Related Accidental Poisoning and Death
Para phenylenediamine (PPD) is a common component of hair dye as well as temporary tattoos and is a well-known cause of type 4 hypersensitivity reactions from topical exposure. While there have been several cases reported in the literature describing toxicities following ingestion, there are a pauci...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159333/ https://www.ncbi.nlm.nih.gov/pubmed/34079664 http://dx.doi.org/10.7759/cureus.14607 |
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author | Gowda, Niraj R Delio, Joseph Elshikh, Amira Khosla, Rahul |
author_facet | Gowda, Niraj R Delio, Joseph Elshikh, Amira Khosla, Rahul |
author_sort | Gowda, Niraj R |
collection | PubMed |
description | Para phenylenediamine (PPD) is a common component of hair dye as well as temporary tattoos and is a well-known cause of type 4 hypersensitivity reactions from topical exposure. While there have been several cases reported in the literature describing toxicities following ingestion, there are a paucity of reports of severe systemic disease following topical exposure. Cases of PPD ingestion have been reported to present with angioedema-like reactions, often progressing to rhabdomyolysis and renal failure. To our knowledge, there have only been two reported cases of severe reactions following topical exposure to PPD. We present a case of a 59-year-old man with topical exposure to hair dye who presented with an angioedema-like reaction shortly after topical exposure to PPD containing hair dye that rapidly progressed to rhabdomyolysis, renal failure, and eventually death. |
format | Online Article Text |
id | pubmed-8159333 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-81593332021-06-01 Hair-Dye-Related Accidental Poisoning and Death Gowda, Niraj R Delio, Joseph Elshikh, Amira Khosla, Rahul Cureus Internal Medicine Para phenylenediamine (PPD) is a common component of hair dye as well as temporary tattoos and is a well-known cause of type 4 hypersensitivity reactions from topical exposure. While there have been several cases reported in the literature describing toxicities following ingestion, there are a paucity of reports of severe systemic disease following topical exposure. Cases of PPD ingestion have been reported to present with angioedema-like reactions, often progressing to rhabdomyolysis and renal failure. To our knowledge, there have only been two reported cases of severe reactions following topical exposure to PPD. We present a case of a 59-year-old man with topical exposure to hair dye who presented with an angioedema-like reaction shortly after topical exposure to PPD containing hair dye that rapidly progressed to rhabdomyolysis, renal failure, and eventually death. Cureus 2021-04-21 /pmc/articles/PMC8159333/ /pubmed/34079664 http://dx.doi.org/10.7759/cureus.14607 Text en Copyright © 2021, Gowda et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Gowda, Niraj R Delio, Joseph Elshikh, Amira Khosla, Rahul Hair-Dye-Related Accidental Poisoning and Death |
title | Hair-Dye-Related Accidental Poisoning and Death |
title_full | Hair-Dye-Related Accidental Poisoning and Death |
title_fullStr | Hair-Dye-Related Accidental Poisoning and Death |
title_full_unstemmed | Hair-Dye-Related Accidental Poisoning and Death |
title_short | Hair-Dye-Related Accidental Poisoning and Death |
title_sort | hair-dye-related accidental poisoning and death |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159333/ https://www.ncbi.nlm.nih.gov/pubmed/34079664 http://dx.doi.org/10.7759/cureus.14607 |
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