Cargando…
Silanol: a bifunctional group for peptide synthesis and late-stage functionalization
Chemical modification of a specific amino acid residue on peptides represents an efficient strategy to improve their pharmacokinetics and facilitates the potential to achieve post-synthetic diversification of peptides. Herein, we reported the first Pd-catalyzed late-stage ortho-olefination of Tyr re...
Autores principales: | Hu, Qi-Long, Hou, Ke-Qiang, Li, Jian, Ge, Yang, Song, Zhen-Dong, Chan, Albert S. C., Xiong, Xiao-Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159358/ https://www.ncbi.nlm.nih.gov/pubmed/34094099 http://dx.doi.org/10.1039/d0sc02439b |
Ejemplares similares
-
Synthesis and Reactivity of the First Isolated Hydrogen‐Bridged Silanol–Silanolate Anions
por: Weitkamp, Robin F., et al.
Publicado: (2020) -
Synthesis of azasilacyclopentenes and silanols via Huisgen cycloaddition-initiated C–H bond insertion cascades
por: Shih, Jiun-Le, et al.
Publicado: (2017) -
The Influence of Weakly Coordinating Cations on the O−H⋅⋅⋅O(−) Hydrogen Bond of Silanol‐Silanolate Anions
por: Weitkamp, Robin F., et al.
Publicado: (2020) -
Selective oxidation of silanes into silanols with water using [MnBr(CO)(5)] as a precatalyst
por: Antico, Emanuele, et al.
Publicado: (2022) -
Nearly free silanols drive the interaction of crystalline silica polymorphs with membranes: Implications for mineral toxicity
por: Pavan, Cristina, et al.
Publicado: (2023)