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Silanol: a bifunctional group for peptide synthesis and late-stage functionalization

Chemical modification of a specific amino acid residue on peptides represents an efficient strategy to improve their pharmacokinetics and facilitates the potential to achieve post-synthetic diversification of peptides. Herein, we reported the first Pd-catalyzed late-stage ortho-olefination of Tyr re...

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Detalles Bibliográficos
Autores principales:	Hu, Qi-Long, Hou, Ke-Qiang, Li, Jian, Ge, Yang, Song, Zhen-Dong, Chan, Albert S. C., Xiong, Xiao-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159358/ https://www.ncbi.nlm.nih.gov/pubmed/34094099 http://dx.doi.org/10.1039/d0sc02439b

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