Chemical synthesis of human syndecan-4 glycopeptide bearing O-, N-sulfation and multiple aspartic acids for probing impacts of the glycan chain and the core peptide on biological functions

Proteoglycans are a family of complex glycoproteins with glycosaminoglycan chains such as heparan sulfate (HS) attached to the core protein backbone. Due to the high structural heterogeneity of HS in nature, it is challenging to decipher the respective roles of the HS chain and the core protein on p...

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Detalles Bibliográficos
Autores principales: Yang, Weizhun, Eken, Yigitcan, Zhang, Jicheng, Cole, Logan Emerson, Ramadan, Sherif, Xu, Yongmei, Zhang, Zeren, Liu, Jian, Wilson, Angela K., Huang, Xuefei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159385/
https://www.ncbi.nlm.nih.gov/pubmed/34094105
http://dx.doi.org/10.1039/d0sc01140a

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