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Dual catalytic enantioselective desymmetrization of allene-tethered cyclohexanones

The construction of enantioenriched azabicyclo[3.3.1]nonan-6-one heterocycles via an enantioselective desymmetrization of allene-linked cyclohexanones, enabled through a dual catalytic system, that provides synchronous activation of the cyclohexanone with a chiral prolinamide and the allene with a c...

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Detalles Bibliográficos
Autores principales:	Zhang, Lin, Yamazaki, Ken, Leitch, Jamie A., Manzano, Ruben, Atkinson, Victoria A. M., Hamlin, Trevor A., Dixon, Darren J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159440/ https://www.ncbi.nlm.nih.gov/pubmed/34123026 http://dx.doi.org/10.1039/d0sc02878a

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