Chimeric oligosaccharide conjugate induces opsonic antibodies against Streptococcus pneumoniae serotypes 19A and 19F

Streptococcus pneumoniae 19A (ST19A) and 19F (ST19F) are among the prevalent serotypes causing pneumococcal disease worldwide even after introduction of a 13-valent pneumococcal conjugate vaccine (PCV13). Synthetic glycoconjugate vaccines have defined chemical structures rather than isolated polysac...

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Detalles Bibliográficos
Autores principales: Sanapala, Someswara Rao, Seco, Bruna M. S., Baek, Ju Yuel, Awan, Shahid I., Pereira, Claney L., Seeberger, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159444/
https://www.ncbi.nlm.nih.gov/pubmed/34123020
http://dx.doi.org/10.1039/d0sc02230f

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