A highly stable RNA aptamer probe for the retinoblastoma protein in live cells

Although RNA aptamers can show comparable or better specificity and affinity to antibodies and have the advantage of being able to access different live cell compartments, they are often much less stable in vivo. We report here the first aptamer that binds human retinoblastoma protein (RB) and is st...

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Detalles Bibliográficos
Autores principales: Le, Thao T., Bruckbauer, Andreas, Tahirbegi, Bogachan, Magness, Alastair J., Ying, Liming, Ellington, Andrew D., Cass, Anthony E. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159449/
https://www.ncbi.nlm.nih.gov/pubmed/34122904
http://dx.doi.org/10.1039/d0sc01613f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159449/
https://www.ncbi.nlm.nih.gov/pubmed/34122904
http://dx.doi.org/10.1039/d0sc01613f

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