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A highly stable RNA aptamer probe for the retinoblastoma protein in live cells
Although RNA aptamers can show comparable or better specificity and affinity to antibodies and have the advantage of being able to access different live cell compartments, they are often much less stable in vivo. We report here the first aptamer that binds human retinoblastoma protein (RB) and is st...
Autores principales: | Le, Thao T., Bruckbauer, Andreas, Tahirbegi, Bogachan, Magness, Alastair J., Ying, Liming, Ellington, Andrew D., Cass, Anthony E. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159449/ https://www.ncbi.nlm.nih.gov/pubmed/34122904 http://dx.doi.org/10.1039/d0sc01613f |
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