ThX – a next-generation probe for the early detection of amyloid aggregates

Neurodegenerative diseases such as Alzheimer's and Parkinson's are associated with protein misfolding and aggregation. Recent studies suggest that the small, rare and heterogeneous oligomeric species, formed early on in the aggregation process, may be a source of cytotoxicity. Thioflavin T...

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Detalles Bibliográficos
Autores principales: Needham, Lisa-Maria, Weber, Judith, Varela, Juan A., Fyfe, James W. B., Do, Dung T., Xu, Catherine K., Tutton, Luke, Cliffe, Rachel, Keenlyside, Benjamin, Klenerman, David, Dobson, Christopher M., Hunter, Christopher A., Müller, Karin H., O'Holleran, Kevin, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159457/
https://www.ncbi.nlm.nih.gov/pubmed/34122915
http://dx.doi.org/10.1039/c9sc04730a

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