[(11)C]PBR28 MR–PET imaging reveals lower regional brain expression of translocator protein (TSPO) in young adult males with autism spectrum disorder

Mechanisms of neuroimmune and mitochondrial dysfunction have been repeatedly implicated in autism spectrum disorder (ASD). To examine these mechanisms in ASD individuals, we measured the in vivo expression of the 18 kDa translocator protein (TSPO), an activated glial marker expressed on mitochondria...

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Detalles Bibliográficos
Autores principales: Zürcher, N. R., Loggia, M. L., Mullett, J. E., Tseng, C., Bhanot, A., Richey, L., Hightower, B. G., Wu, C., Parmar, A. J., Butterfield, R. I., Dubois, J. M., Chonde, D. B., Izquierdo-Garcia, D., Wey, H. Y., Catana, C., Hadjikhani, N., McDougle, C. J., Hooker, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159742/
https://www.ncbi.nlm.nih.gov/pubmed/32076115
http://dx.doi.org/10.1038/s41380-020-0682-z

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