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Loss of DLX3 tumor suppressive function promotes progression of SCC through EGFR-ERBB2 pathway

Cutaneous squamous cell carcinoma (cSCC) ranks second in the frequency of all skin cancers. The balance between keratinocyte proliferation and differentiation is disrupted in the pathological development of cSCC. DLX3 is a homeobox transcription factor which plays pivotal roles in embryonic developm...

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Detalles Bibliográficos
Autores principales: Bajpai, Deepti, Mehdizadeh, Spencer, Uchiyama, Akihiko, Inoue, Yuta, Sawaya, Andrew, Overmiller, Andrew, Brooks, Stephen R., Hasneen, Kowser, Kellett, Meghan, Palazzo, Elisabetta, Motegi, Sei-ichiro, Yuspa, Stuart H., Cataisson, Christophe, Morasso, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159909/
https://www.ncbi.nlm.nih.gov/pubmed/33947961
http://dx.doi.org/10.1038/s41388-021-01802-9

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