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FLT3 mutated acute myeloid leukemia: 2021 treatment algorithm

Approximately 30% of patients with newly diagnosed acute myeloid leukemia (AML) harbor mutations in the fms-like tyrosine kinase 3 (FLT3) gene. While the adverse prognostic impact of FLT3-ITD(mut) in AML has been clearly proven, the prognostic significance of FLT3-TKD(mut) remains speculative. Curre...

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Detalles Bibliográficos
Autores principales: Daver, Naval, Venugopal, Sangeetha, Ravandi, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159924/
https://www.ncbi.nlm.nih.gov/pubmed/34045454
http://dx.doi.org/10.1038/s41408-021-00495-3

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