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GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells
Diabetes is a metabolic syndrome rooted in impaired insulin and/or glucagon secretory responses within the pancreatic islets of Langerhans (islets). Insulin secretion is primarily regulated by two key factors: glucose-mediated ATP production and G-protein coupled receptors (GPCRs) signaling. GPCR ki...
Autores principales: | Snyder, Jonathan, Lackey, Atreju I, Brown, G. Schuyler, Diaz, Melisa, Yuzhen, Tian, Sato, Priscila Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159944/ https://www.ncbi.nlm.nih.gov/pubmed/34045505 http://dx.doi.org/10.1038/s41598-021-90253-z |
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