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Exome sequencing of early-onset patients supports genetic heterogeneity in colorectal cancer
Colorectal cancer (CRC) is a complex disease that can be caused by a spectrum of genetic variants ranging from low to high penetrance changes, that interact with the environment to determine which individuals will develop the disease. In this study, we sequenced 20 early-onset CRC patients to discov...
Autores principales: | Fernández-Rozadilla, C., Álvarez-Barona, M., Quintana, I., López-Novo, A., Amigo, J., Cameselle-Teijeiro, J. M., Roman, E., Gonzalez, D., Llor, X., Bujanda, L., Bessa, X., Jover, R., Balaguer, F., Castells, A., Castellví-Bel, S., Capellá, G., Carracedo, A., Valle, L., Ruiz-Ponte, Clara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159954/ https://www.ncbi.nlm.nih.gov/pubmed/34045552 http://dx.doi.org/10.1038/s41598-021-90590-z |
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