Cargando…

Glutamate connectivity associations converge upon the salience network in schizophrenia and healthy controls

Alterations in cortical inter-areal functional connectivity, and aberrant glutamatergic signalling are implicated in the pathophysiology of schizophrenia but the relationship between the two is unclear. We used multimodal imaging to identify areas of convergence between the two systems. Two separate...

Descripción completa

Detalles Bibliográficos
Autores principales:	McCutcheon, Robert A., Pillinger, Toby, Rogdaki, Maria, Bustillo, Juan, Howes, Oliver D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8159959/ https://www.ncbi.nlm.nih.gov/pubmed/34045446 http://dx.doi.org/10.1038/s41398-021-01455-y

Ejemplares similares

S172. GLUTAMATE RELATED CONNECTIVITY DISTURBANCES OF THE SALIENCE AND DEFAULT MODE NETWORKS IN PSYCHOSIS
por: McCutcheon, Rob, et al.
Publicado: (2020)

Comparative Effects of Antipsychotics on Metabolic and Endocrine Function in Children and Young People With Schizophrenia: A Systematic Review and Network Meta-Analysis
por: Rogdaki, Maria, et al.
Publicado: (2023)

Altered glutamatergic response and functional connectivity in treatment resistant schizophrenia: the effect of riluzole and therapeutic implications
por: Pillinger, Toby, et al.
Publicado: (2019)

T79. BALANCING EFFECTS WITH SIDE-EFFECTS: EXAMINING COMPARATIVE METABOLIC CONSEQUENCES OF 18 ANTIPSYCHOTICS IN TREATMENT OF SCHIZOPHRENIA USING NETWORK META-ANALYSIS
por: Pillinger, Toby, et al.
Publicado: (2020)

F18. IS SCHIZOPHRENIA A MULTI-SYSTEM DISORDER? CONSIDERING NEUROLOGICAL, IMMUNE, CARDIOMETABOLIC, AND ENDOCRINE ALTERATIONS IN FIRST EPISODE PSYCHOSIS
por: Pillinger, Toby, et al.
Publicado: (2018)

Chronic psychosocial stressors are associated with alterations in salience processing and corticostriatal connectivity
por: McCutcheon, Robert A., et al.
Publicado: (2019)

Variability of glucose, insulin, and lipid disturbances in first-episode psychosis: a meta-analysis
por: Pillinger, Toby, et al.
Publicado: (2023)

Antipsychotic plasma levels in the assessment of poor treatment response in schizophrenia
por: McCutcheon, R., et al.
Publicado: (2017)

T45. THE EFFICACY AND HETEROGENEITY OF ANTIPSYCHOTIC RESPONSE IN SCHIZOPHRENIA: A META-ANALYSIS
por: McCutcheon, Rob, et al.
Publicado: (2020)

Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and perspective on potential models
por: Pillinger, Toby, et al.
Publicado: (2018)

Correction to: Is psychosis a multisystem disorder? A meta-review of central nervous system, immune, cardiometabolic, and endocrine alterations in first-episode psychosis and perspective on potential models
por: Pillinger, Toby, et al.
Publicado: (2018)

The Efficacy and Heterogeneity of Antipsychotic Response in Schizophrenia: A Meta-analysis
por: McCutcheon, Robert A., et al.
Publicado: (2021)

Glutamate levels in the anterior cingulate cortex in un-medicated first episode psychosis: a proton magnetic resonance spectroscopy study
por: Borgan, Faith R., et al.
Publicado: (2019)

Mesolimbic Dopamine Function Is Related to Salience Network Connectivity: An Integrative Positron Emission Tomography and Magnetic Resonance Study
por: McCutcheon, Robert A., et al.
Publicado: (2019)

Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis
por: Pillinger, Toby, et al.
Publicado: (2020)

A Meta-analysis of Immune Parameters, Variability, and Assessment of Modal Distribution in Psychosis and Test of the Immune Subgroup Hypothesis
por: Pillinger, Toby, et al.
Publicado: (2019)

Schizophrenia, Dopamine and the Striatum: From Biology to Symptoms
por: McCutcheon, Robert A., et al.
Publicado: (2019)

Inflammation and the neural diathesis-stress hypothesis of schizophrenia: a reconceptualization
por: Howes, O D, et al.
Publicado: (2017)

Magnitude and variability of structural brain abnormalities in neuropsychiatric disease: protocol for a network meta-analysis of MRI studies
por: McCutcheon, Robert, et al.
Publicado: (2021)

Resting-state functional connectivity of salience network in schizophrenia and depression
por: Huang, Huan, et al.
Publicado: (2022)

Defining the Locus of Dopaminergic Dysfunction in Schizophrenia: A Meta-analysis and Test of the Mesolimbic Hypothesis
por: McCutcheon, Robert, et al.
Publicado: (2018)

The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: a cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study
por: Jauhar, Sameer, et al.
Publicado: (2018)

Brain glucose metabolism in schizophrenia: a systematic review and meta-analysis of (18)FDG-PET studies in schizophrenia
por: Townsend, Leigh, et al.
Publicado: (2023)

The relationship between striatal dopamine and anterior cingulate glutamate in first episode psychosis changes with antipsychotic treatment
por: Jauhar, Sameer, et al.
Publicado: (2023)

Sleep and Circadian Rhythm Disturbance in Remitted Schizophrenia and Bipolar Disorder: A Systematic Review and Meta-analysis
por: Meyer, Nicholas, et al.
Publicado: (2020)

The effect of antipsychotics on glutamate levels in the anterior cingulate cortex and clinical response: A (1)H-MRS study in first-episode psychosis patients
por: Zahid, Uzma, et al.
Publicado: (2022)

Heterogeneity and efficacy of antipsychotic treatment for schizophrenia with or without treatment resistance: a meta-analysis
por: Mizuno, Yuya, et al.
Publicado: (2019)

Glutamate in Salience Network Predicts BOLD Response in Default Mode Network During Salience Processing
por: von Düring, Felicia, et al.
Publicado: (2019)

N-Methyl-D-Aspartate Receptor binding in First-Episode Psychosis: A PET brain imaging study
por: Beck, Katherine, et al.
Publicado: (2021)

Disrupted upregulation of salience network connectivity during acute stress in siblings of schizophrenia patients
por: van Leeuwen, Judith M. C., et al.
Publicado: (2021)

Dysregulated but not decreased salience network activity in schizophrenia
por: White, Thomas P., et al.
Publicado: (2013)

The relationship between glutamate, dopamine, and cortical gray matter: A simultaneous PET-MR study
por: Rogeau, Antoine, et al.
Publicado: (2022)

Effective Connectivity between Major Nodes of the Limbic System, Salience and Frontoparietal Networks Differentiates Schizophrenia and Mood Disorders from Healthy Controls
por: Kandilarova, Sevdalina, et al.
Publicado: (2021)

Salience network functional connectivity is spatially heterogeneous across sensorimotor cortex in healthy humans
por: Hegarty, Amy K., et al.
Publicado: (2020)

Functional Convergence in Reduced Genomes of Bacterial Symbionts Spanning 200 My of Evolution
por: McCutcheon, John P., et al.
Publicado: (2010)

The Relationship Between Frontostriatal Connectivity and Striatal Dopamine Function in Schizophrenia: An (18)F-DOPA PET and Diffusion Tensor Imaging Study in Treatment Responsive and Resistant Patients
por: Shin, Sangho, et al.
Publicado: (2022)

Corrigendum: Dysregulated but not decreased salience network activity in schizophrenia
por: White, Thomas P., et al.
Publicado: (2019)

M149. THE TOPOGRAPHY OF STRIATAL DOPAMINE AND SYMPTOMS IN PSYCHOSIS: AN INTEGRATIVE PET AND MRI STUDY
por: McCutcheon, Rob, et al.
Publicado: (2020)

Effective connectivity of the right anterior insula in schizophrenia: The salience network and task-negative to task-positive transition
por: Luo, Qiang, et al.
Publicado: (2020)

S154. THE ROLE OF DOPAMINE IN PROCESSING THE MEANINGFUL INFORMATION OF OBSERVATIONS, AND IMPLICATIONS FOR THE ABERRANT SALIENCE HYPOTHESIS OF SCHIZOPHRENIA
por: Nour, Matthew, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_kusfttja6qidgprdl1k8k3jbi3