Expression of the myeloid inhibitory receptor CLEC12A correlates with disease activity and cytokines in early rheumatoid arthritis

The myeloid inhibitory receptor CLEC12A negatively regulates inflammation. Reduced CLEC12A expression enhances inflammation in CLEC12A knock-out mice with collagen antibody-induced arthritis. Moreover, CLEC12A internalisation augments human neutrophil activation. We thus postulated that CLEC12A expr...

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Detalles Bibliográficos
Autores principales: Vaillancourt, Myriam, Desaulniers, Philippe, Paré, Guillaume, Pagé, Nathalie, Lachhab , Asmaa, Kerever, Anthony, Julien, Anne-Sophie, Amiable, Nathalie, Pelletier, Martin, Tessier, Philippe A., Bessette, Louis, Michou, Laëtitia, Fortin, Paul R., Fernandes, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160002/
https://www.ncbi.nlm.nih.gov/pubmed/34045571
http://dx.doi.org/10.1038/s41598-021-90631-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160002/
https://www.ncbi.nlm.nih.gov/pubmed/34045571
http://dx.doi.org/10.1038/s41598-021-90631-7

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