Monocyte-Derived Macrophages Contribute to Chitinase Dysregulation in Amyotrophic Lateral Sclerosis: A Pilot Study

Neuroinflammation significantly contributes to Amyotrophic Lateral Sclerosis (ALS) pathology. In lieu of this, reports of elevated chitinase levels in ALS are interesting, as they are established surrogate markers of a chronic inflammatory response. While post-mortem studies have indicated glial exp...

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Detalles Bibliográficos
Autores principales: Gaur, Nayana, Huss, Elena, Prell, Tino, Steinbach, Robert, Guerra, Joel, Srivastava, Akash, Witte, Otto W., Grosskreutz, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160083/
https://www.ncbi.nlm.nih.gov/pubmed/34054686
http://dx.doi.org/10.3389/fneur.2021.629332

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