Cargando…

Endothelial Dysfunction and Impaired Neurovascular Coupling Responses Precede Cognitive Impairment in a Mouse Model of Geriatric Sepsis

Sepsis is a life-threatening condition, the incidence of which is significantly increased in elderly patients. One of the long-lasting effects of sepsis is cognitive impairment defined as a new deficit or exacerbation of preexisting deficits in global cognition or executive function. Normal brain fu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Csipo, Tamas, Cassidy, Benjamin R., Balasubramanian, Priya, Drevets, Douglas A., Ungvari, Zoltan I., Yabluchanskiy, Andriy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Aging Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160114/ https://www.ncbi.nlm.nih.gov/pubmed/34054502 http://dx.doi.org/10.3389/fnagi.2021.644733

Ejemplares similares

Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses
por: Csipo, Tamas, et al.
Publicado: (2021)

Fusogenic Liposomes Deliver Resveratrol to Brain Microcirculation and Improve Neurovascular Coupling in Aged Mice
por: Toth, Adam Nyul, et al.
Publicado: (2020)

NMN Rescues Endothelial Function and Neurovascular Coupling, Improving Cognitive Function in Aged Mice
por: Tarantini, Stefano, et al.
Publicado: (2020)

Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults
por: Csipo, Tamas, et al.
Publicado: (2021)

Age-related decline in circulating IGF-1 associates with impaired neurovascular coupling responses in older adults
por: Toth, Luca, et al.
Publicado: (2022)

Sex differences in brain functional connectivity of hippocampus in mild cognitive impairment
por: Williamson, Jordan, et al.
Publicado: (2022)

Gait variability predicts cognitive impairment in older adults with subclinical cerebral small vessel disease
por: Mukli, Peter, et al.
Publicado: (2022)

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
por: Tarantini, Stefano, et al.
Publicado: (2019)

Retinal biomarkers for Alzheimer’s disease and vascular cognitive impairment and dementia (VCID): implication for early diagnosis and prognosis
por: Czakó, Cecilia, et al.
Publicado: (2020)

Imaging retinal microvascular manifestations of carotid artery disease in older adults: from diagnosis of ocular complications to understanding microvascular contributions to cognitive impairment
por: István, Lilla, et al.
Publicado: (2021)

Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation
por: Ungvari, Zoltan, et al.
Publicado: (2019)

Integrative Role of Hyperbaric Oxygen Therapy on Healthspan, Age-Related Vascular Cognitive Impairment, and Dementia
por: Balasubramanian, Priya, et al.
Publicado: (2021)

Treatment with the mitochondrial‐targeted antioxidant peptide SS‐31 rescues neurovascular coupling responses and cerebrovascular endothelial function and improves cognition in aged mice
por: Tarantini, Stefano, et al.
Publicado: (2018)

Progerin-Induced Impairment in Wound Healing and Proliferation in Vascular Endothelial Cells
por: Jiang, Yizhi, et al.
Publicado: (2022)

IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging
por: Toth, Peter, et al.
Publicado: (2015)

The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment
por: Ungvari, Anna, et al.
Publicado: (2023)

Impact of impaired cerebral blood flow autoregulation on cognitive impairment
por: Wang, Shaoxun, et al.
Publicado: (2022)

Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging
por: Miller, Lauren R., et al.
Publicado: (2022)

Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment
por: Fernández, Alba, et al.
Publicado: (2022)

Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer’s disease
por: Zhukov, Oleg, et al.
Publicado: (2023)

Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain
por: Ahire, Chetan, et al.
Publicado: (2023)

The role of endothelial TRP channels in age-related vascular cognitive impairment and dementia
por: Negri, Sharon, et al.
Publicado: (2023)

Subarachnoid Hemorrhage, Spreading Depolarizations and Impaired Neurovascular Coupling
por: Koide, Masayo, et al.
Publicado: (2013)

Age-Dependent Impairment of Neurovascular and Neurometabolic Coupling in the Hippocampus
por: Lourenço, Cátia F., et al.
Publicado: (2018)

Sex-specific hippocampal connectivity markers in mild cognitive impairment
por: Yang, Yuan, et al.
Publicado: (2023)

Neurovascular Coupling Impairment in Heart Failure with Reduction Ejection Fraction
por: Aires, Ana, et al.
Publicado: (2020)

The retinal neurovascular coupling is impaired in men with vasculogenic erectile dysfunction
por: Borrelli, Enrico, et al.
Publicado: (2023)

Endoplasmic Reticulum Stress and miRNA Impairment in Aging and Age-Related Diseases
por: Demirel-Yalciner, Tugce, et al.
Publicado: (2022)

Identifying Cognitive Impairment in Elderly Using Coupling Functions Between Cerebral Oxyhemoglobin and Arterial Blood Pressure
por: Li, Wenhao, et al.
Publicado: (2022)

Urinary Biomarkers of Oxidative Stress in Aging: Implications for Prediction of Accelerated Biological Age in Prospective Cohort Studies
por: Mukli, Peter, et al.
Publicado: (2022)

Episodic Memory Impairment Mediates the Loss of Awareness in Mild Cognitive Impairment
por: Gagliardi, Geoffroy, et al.
Publicado: (2022)

Chronic blue light leads to accelerated aging in Drosophila by impairing energy metabolism and neurotransmitter levels
por: Yang, Jun, et al.
Publicado: (2022)

Impaired Hippocampal Neurovascular Coupling in a Mouse Model of Alzheimer’s Disease
por: Li, Lin, et al.
Publicado: (2021)

Convergent functional changes of the episodic memory impairment in mild cognitive impairment: An ALE meta-analysis
por: Liang, Xuhong, et al.
Publicado: (2022)

Impaired fasting glucose, oxidative distress, and cognitive impairment. Is this the starting point on DBT cognitive decline?
por: Canal, María Pilar, et al.
Publicado: (2022)

Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study
por: Owens, Cameron D., et al.
Publicado: (2023)

Editorial: The Neurovascular Unit as a Potential Biomarker and Therapeutic Target in Cerebrovascular Disease
por: Nizari, Shereen, et al.
Publicado: (2022)

A two-year longitudinal study of retinal vascular impairment in patients with amnestic mild cognitive impairment
por: Criscuolo, Chiara, et al.
Publicado: (2022)

Mild behavioral impairment linked to progression to Alzheimer’s disease and cortical thinning in amnestic mild cognitive impairment
por: Yoon, Eun Jin, et al.
Publicado: (2023)

G-quadruplexes Stabilization Upregulates CCN1 and Accelerates Aging in Cultured Cerebral Endothelial Cells
por: Noh, Brian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rjdkmqfpcvercmek0r5o95njto