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Delayed manifestation of extensive COVID-19-associated coagulopathy in high-risk patient
COVID-19 is an infectious disease caused by the novel coronavirus. It presents as an acute respiratory illness, however, it also affects multiple other organ systems. One such unique manifestation is systemic coagulopathy involving arterial and venous systems. We present a 29-year-old woman with Hod...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160192/ https://www.ncbi.nlm.nih.gov/pubmed/34039554 http://dx.doi.org/10.1136/bcr-2021-242921 |
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author | Sharma, Purva Chakraborty, Kanishka |
author_facet | Sharma, Purva Chakraborty, Kanishka |
author_sort | Sharma, Purva |
collection | PubMed |
description | COVID-19 is an infectious disease caused by the novel coronavirus. It presents as an acute respiratory illness, however, it also affects multiple other organ systems. One such unique manifestation is systemic coagulopathy involving arterial and venous systems. We present a 29-year-old woman with Hodgkin’s lymphoma, who was diagnosed with COVID-19 infection prior to initiating chemotherapy. Two months after resolution of symptoms and testing negative for COVID-19, she presented with multiple acute thromboembolic complications of the infection, including bilateral jugular venous thrombosis, right atrial clot and arterial emboli in the brain resulting in cerebrovascular injury. These were thought to be delayed manifestations of the systemic coagulopathy secondary to infection. Also, some of these thromboembolic phenomena occurred while the patient was on anticoagulation, which emphasises the extensive hyperinflammatory state caused by the virus. This case highlights the importance of thromboprophylaxis especially in high-risk patients with this infection. |
format | Online Article Text |
id | pubmed-8160192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-81601922021-06-10 Delayed manifestation of extensive COVID-19-associated coagulopathy in high-risk patient Sharma, Purva Chakraborty, Kanishka BMJ Case Rep Case Report COVID-19 is an infectious disease caused by the novel coronavirus. It presents as an acute respiratory illness, however, it also affects multiple other organ systems. One such unique manifestation is systemic coagulopathy involving arterial and venous systems. We present a 29-year-old woman with Hodgkin’s lymphoma, who was diagnosed with COVID-19 infection prior to initiating chemotherapy. Two months after resolution of symptoms and testing negative for COVID-19, she presented with multiple acute thromboembolic complications of the infection, including bilateral jugular venous thrombosis, right atrial clot and arterial emboli in the brain resulting in cerebrovascular injury. These were thought to be delayed manifestations of the systemic coagulopathy secondary to infection. Also, some of these thromboembolic phenomena occurred while the patient was on anticoagulation, which emphasises the extensive hyperinflammatory state caused by the virus. This case highlights the importance of thromboprophylaxis especially in high-risk patients with this infection. BMJ Publishing Group 2021-05-26 /pmc/articles/PMC8160192/ /pubmed/34039554 http://dx.doi.org/10.1136/bcr-2021-242921 Text en © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. https://bmj.com/coronavirus/usageThis article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. |
spellingShingle | Case Report Sharma, Purva Chakraborty, Kanishka Delayed manifestation of extensive COVID-19-associated coagulopathy in high-risk patient |
title | Delayed manifestation of extensive COVID-19-associated coagulopathy in high-risk patient |
title_full | Delayed manifestation of extensive COVID-19-associated coagulopathy in high-risk patient |
title_fullStr | Delayed manifestation of extensive COVID-19-associated coagulopathy in high-risk patient |
title_full_unstemmed | Delayed manifestation of extensive COVID-19-associated coagulopathy in high-risk patient |
title_short | Delayed manifestation of extensive COVID-19-associated coagulopathy in high-risk patient |
title_sort | delayed manifestation of extensive covid-19-associated coagulopathy in high-risk patient |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160192/ https://www.ncbi.nlm.nih.gov/pubmed/34039554 http://dx.doi.org/10.1136/bcr-2021-242921 |
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