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5-LO-derived LTB4 plays a key role in MCP-1 expression in HMGB1-exposed VSMCs via a BLTR1 signaling axis

Monocyte chemoattractant protein-1 (MCP-1) plays an important role in initiating vascular inflammation; however, its cellular source in the injured vasculatures is unclear. Given the importance of high mobility group box 1 (HMGB1) in tissue injury, we investigated the role of vascular smooth muscle...

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Detalles Bibliográficos
Autores principales: Choi, Jong Min, Baek, Seung Eun, Kim, Ji On, Jeon, Eun Yeong, Jang, Eun Jeong, Kim, Chi Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160259/
https://www.ncbi.nlm.nih.gov/pubmed/34045591
http://dx.doi.org/10.1038/s41598-021-90636-2

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