Identification of Mutator-Derived Alternative Splicing Signatures of Genomic Instability for Improving the Clinical Outcome of Cholangiocarcinoma

BACKGROUND: Cholangiocarcinoma is an aggressive carcinoma with increasing incidence and poor outcomes worldwide. Genomic instability and alternative splicing (AS) events are hallmarks of carcinoma development and progression. The relationship between genomic instability, AS events, and tumor immune...

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Detalles Bibliográficos
Autores principales: Lin, Zijing, Gong, Jianping, Zhong, Guochao, Hu, Jiejun, Cai, Dong, Zhao, Lei, Zhao, Zhibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160381/
https://www.ncbi.nlm.nih.gov/pubmed/34055632
http://dx.doi.org/10.3389/fonc.2021.666847

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