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DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A

Oncogene-induced senescence (OIS) is a stable cell cycle arrest that occurs in normal cells upon oncogene activation. Cells undergoing OIS express a wide variety of secreted factors that affect the senescent microenvironment termed the senescence-associated secretory phenotype (SASP), which is benef...

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Detalles Bibliográficos
Autores principales:	Leon, Kelly E., Buj, Raquel, Lesko, Elizabeth, Dahl, Erika S., Chen, Chi-Wei, Tangudu, Naveen Kumar, Imamura-Kawasawa, Yuka, Kossenkov, Andrew V., Hobbs, Ryan P., Aird, Katherine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160577/ https://www.ncbi.nlm.nih.gov/pubmed/34037658 http://dx.doi.org/10.1083/jcb.202008101

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