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LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components
After two converging DNA replication forks meet, active replisomes are disassembled and unloaded from chromatin. A key process in replisome disassembly is the unloading of CMG helicases (CDC45–MCM–GINS), which is initiated in Caenorhabditis elegans and Xenopus laevis by the E3 ubiquitin ligase CRL2(...
Autores principales: | Fan, Yilin, Köberlin, Marielle S., Ratnayeke, Nalin, Liu, Chad, Deshpande, Madhura, Gerhardt, Jeannine, Meyer, Tobias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160578/ https://www.ncbi.nlm.nih.gov/pubmed/34037657 http://dx.doi.org/10.1083/jcb.202009147 |
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