A Potential Role for HUWE1 in Modulating Cisplatin Sensitivity

Cisplatin is a widely used antineoplastic agent, whose efficacy is limited by primary and acquired therapeutic resistance. Recently, a bladder cancer genome-wide CRISPR/Cas9 knock-out screen correlated cisplatin sensitivity to multiple genetic biomarkers. Among the screen’s top hits was the HECT dom...

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Detalles Bibliográficos
Autores principales: Wenmaekers, Stijn, Viergever, Bastiaan J., Kumar, Gunjan, Kranenburg, Onno, Black, Peter C., Daugaard, Mads, Meijer, Richard P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160634/
https://www.ncbi.nlm.nih.gov/pubmed/34065298
http://dx.doi.org/10.3390/cells10051262

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