Cargando…

Regional Differences in Heat Shock Protein 25 Expression in Brain and Spinal Cord Astrocytes of Wild-Type and SOD1 (G93A) Mice

Heterogeneity of glia in different CNS regions may contribute to the selective vulnerability of neuronal populations in neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS). Here, we explored regional variations in the expression of heat shock protein 25 in glia under conditions...

Descripción completa

Detalles Bibliográficos
Autores principales:	San Gil, Rebecca, Clarke, Benjamin E., Ecroyd, Heath, Kalmar, Bernadett, Greensmith, Linda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160835/ https://www.ncbi.nlm.nih.gov/pubmed/34069691 http://dx.doi.org/10.3390/cells10051257

Ejemplares similares

Regional differences in the inflammatory and heat shock response in glia: implications for ALS
por: Clarke, Benjamin E., et al.
Publicado: (2019)

Activation of the heat shock response in a primary cellular model of motoneuron neurodegeneration-evidence for neuroprotective and neurotoxic effects
por: Kalmar, Bernadett, et al.
Publicado: (2009)

Plasma Neurofilament Heavy Chain Levels Correlate to Markers of Late Stage Disease Progression and Treatment Response in SOD1(G93A) Mice that Model ALS
por: Lu, Ching-Hua, et al.
Publicado: (2012)

Molecular Chaperone Mediated Late-Stage Neuroprotection in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
por: Novoselov, Sergey S., et al.
Publicado: (2013)

Using bicistronic constructs to evaluate the chaperone activities of heat shock proteins in cells
por: San Gil, Rebecca, et al.
Publicado: (2017)

The heat shock response in neurons and astroglia and its role in neurodegenerative diseases
por: San Gil, Rebecca, et al.
Publicado: (2017)

A comprehensive assessment of the SOD1(G93A) low-copy transgenic mouse, which models human amyotrophic lateral sclerosis
por: Acevedo-Arozena, Abraham, et al.
Publicado: (2011)

Histamine Is an Inducer of the Heat Shock Response in SOD1-G93A Models of ALS
por: Apolloni, Savina, et al.
Publicado: (2019)

Enhanced Expression of TRAP1 Protects Mitochondrial Function in Motor Neurons under Conditions of Oxidative Stress
por: Clarke, Benjamin E., et al.
Publicado: (2022)

Cellular Chaperones As Therapeutic Targets in ALS to Restore Protein Homeostasis and Improve Cellular Function
por: Kalmar, Bernadett, et al.
Publicado: (2017)

Neuronal–glial communication perturbations in murine SOD1(G93A) spinal cord
por: MacLean, Michael, et al.
Publicado: (2022)

Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1(G93A) Transgenic Mice
por: Cai, MuDan, et al.
Publicado: (2018)

Altered Metabolic Profiles Associate with Toxicity in SOD1(G93A) Astrocyte-Neuron Co-Cultures
por: Valbuena, Gabriel N., et al.
Publicado: (2017)

Inhibition of heat shock proteins increases autophagosome formation, and reduces the expression of APP, Tau, SOD1 G93A and TDP-43
por: Dent, Paul, et al.
Publicado: (2021)

Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1 (G93A) mouse model of amyotrophic lateral sclerosis
por: Baker, David J., et al.
Publicado: (2015)

Molecular Dynamics Analysis of Apolipoprotein-D - Lipid Hydroperoxide Interactions: Mechanism for Selective Oxidation of Met-93
por: Oakley, Aaron J., et al.
Publicado: (2012)

Cu(II)(atsm) improves the neurological phenotype and survival of SOD1(G93A) mice and selectively increases enzymatically active SOD1 in the spinal cord
por: Hilton, James B., et al.
Publicado: (2017)

Human Glial-Restricted Progenitor Transplantation into Cervical Spinal Cord of the SOD1(G93A) Mouse Model of ALS
por: Lepore, Angelo C., et al.
Publicado: (2011)

Preliminary Observation about Alteration of Proteins and Their Potential Functions in Spinal Cord of SOD1 G93A Transgenic Mice
por: Zhang, Jie, et al.
Publicado: (2018)

Spinal Cord Metabolic Signatures in Models of Fast- and Slow-Progressing SOD1(G93A) Amyotrophic Lateral Sclerosis
por: Valbuena, Gabriel N., et al.
Publicado: (2019)

Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing
por: Carroll, Jean, et al.
Publicado: (2015)

Administration of Recombinant Heat Shock Protein 70 Delays Peripheral Muscle Denervation in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
por: Gifondorwa, David J., et al.
Publicado: (2012)

Perturbations of the Proteome and of Secreted Metabolites in Primary Astrocytes from the hSOD1(G93A) ALS Mouse Model
por: Stella, Roberto, et al.
Publicado: (2021)

Mitochondria-Targeted Catalase Reverts the Neurotoxicity of hSOD1(G93A) Astrocytes without Extending the Survival of ALS-Linked Mutant hSOD1 Mice
por: Pehar, Mariana, et al.
Publicado: (2014)

Early gene expression changes in spinal cord from SOD1(G93A) Amyotrophic Lateral Sclerosis animal model
por: de Oliveira, Gabriela P., et al.
Publicado: (2013)

Changes in the Expression of FUS/TLS in Spinal Cords of SOD1 G93A Transgenic Mice and Correlation with Motor-Neuron Degeneration
por: Li, Jiao, et al.
Publicado: (2016)

ALS-Associated SOD1(G93A) Decreases SERCA Pump Levels and Increases Store-Operated Ca(2+) Entry in Primary Spinal Cord Astrocytes from a Transgenic Mouse Model
por: Norante, Rosa Pia, et al.
Publicado: (2019)

Comparison of dendritic calcium transients in juvenile wild type and SOD1(G93A) mouse lumbar motoneurons
por: Quinlan, Katharina A., et al.
Publicado: (2015)

Trophic and proliferative effects of Shh on motor neurons in embryonic spinal cord culture from wildtype and G93A SOD1 mice
por: Ma, Xiaoxing, et al.
Publicado: (2013)

Oxaloacetate treatment preserves motor function in SOD1(G93A) mice and normalizes select neuroinflammation-related parameters in the spinal cord
por: Tungtur, Sudheer K., et al.
Publicado: (2021)

Modulation of SOD1 Subcellular Localization by Transfection with Wild- or Mutant-type SOD1 in Primary Neuron and Astrocyte Cultures from ALS Mice
por: Lee, Do-Yeon, et al.
Publicado: (2015)

Monoaminergic control of spinal locomotor networks in SOD1(G93A) newborn mice
por: Milan, Léa, et al.
Publicado: (2014)

Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis
por: Taha, Doaa M, et al.
Publicado: (2022)

Neuromuscular effects of G93A-SOD1 expression in zebrafish
por: Sakowski, Stacey A, et al.
Publicado: (2012)

The 2-Oxoglutarate Carrier Is S-Nitrosylated in the Spinal Cord of G93A Mutant hSOD1 Mice Resulting in Disruption of Mitochondrial Glutathione Transport
por: Linseman, Daniel A., et al.
Publicado: (2022)

In vivo imaging of axonal transport in murine motor and sensory neurons
por: Gibbs, Katherine L., et al.
Publicado: (2016)

Immune response in peripheral axons delays disease progression in SOD1(G93A) mice
por: Nardo, Giovanni, et al.
Publicado: (2016)

Safety and efficacy of human embryonic stem cell-derived astrocytes following intrathecal transplantation in SOD1(G93A) and NSG animal models
por: Izrael, Michal, et al.
Publicado: (2018)

Comparative analysis of the time-dependent functional and molecular changes in spinal cord degeneration induced by the G93A SOD1 gene mutation and by mechanical compression
por: Malaspina, Andrea, et al.
Publicado: (2008)

Deregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1(G93A) Amyotrophic Lateral Sclerosis mouse model
por: Maximino, Jessica R., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6mth603nnrrdp80j2l2qh7p7aa