A Review of Mathematics Determining Solute Uptake at the Blood–Brain Barrier in Normal and Pathological Conditions

The blood–brain barrier (BBB) limits movement of solutes from the lumen of the brain microvascular capillary system into the parenchyma. The unidirectional transfer constant, K(in), is the rate at which transport across the BBB occurs for individual molecules. Single and multiple uptake experiments...

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Detalles Bibliográficos
Autores principales: Sprowls, Samuel A., Saralkar, Pushkar, Arsiwala, Tasneem, Adkins, Christopher E., Blethen, Kathryn E., Pizzuti, Vincenzo J., Shah, Neal, Fladeland, Ross, Lockman, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160855/
https://www.ncbi.nlm.nih.gov/pubmed/34069733
http://dx.doi.org/10.3390/pharmaceutics13050756

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