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The Tumor Microenvironment in Follicular Lymphoma: Its Pro-Malignancy Role with Therapeutic Potential
In the follicular lymphoma (FL) microenvironment, CXCR5(+)ICOS(+)PD1(+)BCL6(+) follicular helper T (Tfh) cells, which closely correlate with FL B cells in neoplastic follicles, play a major role in supporting FL. Interleukin-4 secreted by Tfh cells triggers the upregulation of the lymphocyte chemoat...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160856/ https://www.ncbi.nlm.nih.gov/pubmed/34069564 http://dx.doi.org/10.3390/ijms22105352 |