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Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention

In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high b...

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Detalles Bibliográficos
Autores principales: Al-Anbaki, Marwah, Cavin, Anne-Laure, Nogueira, Renata Campos, Taslimi, Jaafar, Ali, Hayder, Najem, Mohammed, Shukur Mahmood, Mustafa, Abdullah Khaleel, Ibrahim, Saad Mohammed, Abdulqader, Ramadhan Hasan, Hasan, Marcourt, Laurence, Félix, Fabien, Vinh Tri Low-Der’s, Nicolas, Ferreira Queiroz, Emerson, Wolfender, Jean-Luc, Watissée, Marie, Graz, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160910/
https://www.ncbi.nlm.nih.gov/pubmed/34069702
http://dx.doi.org/10.3390/plants10051018
Descripción
Sumario:In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received HS decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (n = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group (n = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product.