Cargando…

Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention

In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high b...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Anbaki, Marwah, Cavin, Anne-Laure, Nogueira, Renata Campos, Taslimi, Jaafar, Ali, Hayder, Najem, Mohammed, Shukur Mahmood, Mustafa, Abdullah Khaleel, Ibrahim, Saad Mohammed, Abdulqader, Ramadhan Hasan, Hasan, Marcourt, Laurence, Félix, Fabien, Vinh Tri Low-Der’s, Nicolas, Ferreira Queiroz, Emerson, Wolfender, Jean-Luc, Watissée, Marie, Graz, Bertrand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160910/
https://www.ncbi.nlm.nih.gov/pubmed/34069702
http://dx.doi.org/10.3390/plants10051018
_version_ 1783700390969081856
author Al-Anbaki, Marwah
Cavin, Anne-Laure
Nogueira, Renata Campos
Taslimi, Jaafar
Ali, Hayder
Najem, Mohammed
Shukur Mahmood, Mustafa
Abdullah Khaleel, Ibrahim
Saad Mohammed, Abdulqader
Ramadhan Hasan, Hasan
Marcourt, Laurence
Félix, Fabien
Vinh Tri Low-Der’s, Nicolas
Ferreira Queiroz, Emerson
Wolfender, Jean-Luc
Watissée, Marie
Graz, Bertrand
author_facet Al-Anbaki, Marwah
Cavin, Anne-Laure
Nogueira, Renata Campos
Taslimi, Jaafar
Ali, Hayder
Najem, Mohammed
Shukur Mahmood, Mustafa
Abdullah Khaleel, Ibrahim
Saad Mohammed, Abdulqader
Ramadhan Hasan, Hasan
Marcourt, Laurence
Félix, Fabien
Vinh Tri Low-Der’s, Nicolas
Ferreira Queiroz, Emerson
Wolfender, Jean-Luc
Watissée, Marie
Graz, Bertrand
author_sort Al-Anbaki, Marwah
collection PubMed
description In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received HS decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (n = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group (n = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product.
format Online
Article
Text
id pubmed-8160910
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-81609102021-05-29 Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention Al-Anbaki, Marwah Cavin, Anne-Laure Nogueira, Renata Campos Taslimi, Jaafar Ali, Hayder Najem, Mohammed Shukur Mahmood, Mustafa Abdullah Khaleel, Ibrahim Saad Mohammed, Abdulqader Ramadhan Hasan, Hasan Marcourt, Laurence Félix, Fabien Vinh Tri Low-Der’s, Nicolas Ferreira Queiroz, Emerson Wolfender, Jean-Luc Watissée, Marie Graz, Bertrand Plants (Basel) Article In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received HS decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (n = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group (n = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product. MDPI 2021-05-19 /pmc/articles/PMC8160910/ /pubmed/34069702 http://dx.doi.org/10.3390/plants10051018 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Al-Anbaki, Marwah
Cavin, Anne-Laure
Nogueira, Renata Campos
Taslimi, Jaafar
Ali, Hayder
Najem, Mohammed
Shukur Mahmood, Mustafa
Abdullah Khaleel, Ibrahim
Saad Mohammed, Abdulqader
Ramadhan Hasan, Hasan
Marcourt, Laurence
Félix, Fabien
Vinh Tri Low-Der’s, Nicolas
Ferreira Queiroz, Emerson
Wolfender, Jean-Luc
Watissée, Marie
Graz, Bertrand
Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
title Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
title_full Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
title_fullStr Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
title_full_unstemmed Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
title_short Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
title_sort hibiscus sabdariffa, a treatment for uncontrolled hypertension. pilot comparative intervention
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160910/
https://www.ncbi.nlm.nih.gov/pubmed/34069702
http://dx.doi.org/10.3390/plants10051018
work_keys_str_mv AT alanbakimarwah hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT cavinannelaure hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT nogueirarenatacampos hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT taslimijaafar hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT alihayder hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT najemmohammed hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT shukurmahmoodmustafa hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT abdullahkhaleelibrahim hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT saadmohammedabdulqader hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT ramadhanhasanhasan hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT marcourtlaurence hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT felixfabien hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT vinhtrilowdersnicolas hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT ferreiraqueirozemerson hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT wolfenderjeanluc hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT watisseemarie hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention
AT grazbertrand hibiscussabdariffaatreatmentforuncontrolledhypertensionpilotcomparativeintervention