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Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high b...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160910/ https://www.ncbi.nlm.nih.gov/pubmed/34069702 http://dx.doi.org/10.3390/plants10051018 |
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author | Al-Anbaki, Marwah Cavin, Anne-Laure Nogueira, Renata Campos Taslimi, Jaafar Ali, Hayder Najem, Mohammed Shukur Mahmood, Mustafa Abdullah Khaleel, Ibrahim Saad Mohammed, Abdulqader Ramadhan Hasan, Hasan Marcourt, Laurence Félix, Fabien Vinh Tri Low-Der’s, Nicolas Ferreira Queiroz, Emerson Wolfender, Jean-Luc Watissée, Marie Graz, Bertrand |
author_facet | Al-Anbaki, Marwah Cavin, Anne-Laure Nogueira, Renata Campos Taslimi, Jaafar Ali, Hayder Najem, Mohammed Shukur Mahmood, Mustafa Abdullah Khaleel, Ibrahim Saad Mohammed, Abdulqader Ramadhan Hasan, Hasan Marcourt, Laurence Félix, Fabien Vinh Tri Low-Der’s, Nicolas Ferreira Queiroz, Emerson Wolfender, Jean-Luc Watissée, Marie Graz, Bertrand |
author_sort | Al-Anbaki, Marwah |
collection | PubMed |
description | In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received HS decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (n = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group (n = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product. |
format | Online Article Text |
id | pubmed-8160910 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81609102021-05-29 Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention Al-Anbaki, Marwah Cavin, Anne-Laure Nogueira, Renata Campos Taslimi, Jaafar Ali, Hayder Najem, Mohammed Shukur Mahmood, Mustafa Abdullah Khaleel, Ibrahim Saad Mohammed, Abdulqader Ramadhan Hasan, Hasan Marcourt, Laurence Félix, Fabien Vinh Tri Low-Der’s, Nicolas Ferreira Queiroz, Emerson Wolfender, Jean-Luc Watissée, Marie Graz, Bertrand Plants (Basel) Article In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP); medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received HS decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (n = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group (n = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product. MDPI 2021-05-19 /pmc/articles/PMC8160910/ /pubmed/34069702 http://dx.doi.org/10.3390/plants10051018 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Al-Anbaki, Marwah Cavin, Anne-Laure Nogueira, Renata Campos Taslimi, Jaafar Ali, Hayder Najem, Mohammed Shukur Mahmood, Mustafa Abdullah Khaleel, Ibrahim Saad Mohammed, Abdulqader Ramadhan Hasan, Hasan Marcourt, Laurence Félix, Fabien Vinh Tri Low-Der’s, Nicolas Ferreira Queiroz, Emerson Wolfender, Jean-Luc Watissée, Marie Graz, Bertrand Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention |
title | Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention |
title_full | Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention |
title_fullStr | Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention |
title_full_unstemmed | Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention |
title_short | Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention |
title_sort | hibiscus sabdariffa, a treatment for uncontrolled hypertension. pilot comparative intervention |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160910/ https://www.ncbi.nlm.nih.gov/pubmed/34069702 http://dx.doi.org/10.3390/plants10051018 |
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