Cargando…

Pharmacodynamic Evaluation of a Single Dose versus a 24-Hour Course of Multiple Doses of Cefazolin for Surgical Prophylaxis

The optimal perioperative duration for the administration of cefazolin and other prophylactic antibiotics remains unclear. This study aimed to describe the pharmacodynamics of cefazolin for a single 2 g dose versus a 24 h course of a 2 g single dose plus a 1 g eight-hourly regimen against methicilli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Heffernan, Aaron, Alawie, Jowana, Wallis, Steven C, Naicker, Saiyuri, Adiraju, Santosh, Roberts, Jason A., Sime, Fekade Bruck
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161008/ https://www.ncbi.nlm.nih.gov/pubmed/34069492 http://dx.doi.org/10.3390/antibiotics10050602

Ejemplares similares

Evaluation of Fosfomycin-Sulbactam Combination Therapy against Carbapenem-Resistant Acinetobacter baumannii Isolates in a Hollow-Fibre Infection Model
por: Mohd Sazlly Lim, Sazlyna, et al.
Publicado: (2022)

Impact of the Epithelial Lining Fluid Milieu on Amikacin Pharmacodynamics Against Pseudomonas aeruginosa
por: Heffernan, Aaron J., et al.
Publicado: (2021)

Evaluating Mono- and Combination Therapy of Meropenem and Amikacin against Pseudomonas aeruginosa Bacteremia in the Hollow-Fiber Infection Model
por: Avent, Minyon L., et al.
Publicado: (2022)

1097. An Antimicrobial Stewardship Intervention to Optimize Cefazolin Dosing for Surgical Prophylaxis
por: Neuner, Elizabeth A, et al.
Publicado: (2019)

Pharmacokinetics and Optimal Dose Selection of Cefazolin for Surgical Prophylaxis of Pediatric Patients
por: Schmitz, Michael L., et al.
Publicado: (2020)

A randomized controlled trial to compare antibiotic prophylaxis in elective gynecological surgeries: Single dose of cefazolin versus single dose of cefazolin and tinidazole
por: Garg, Shivani, et al.
Publicado: (2021)

Single dose cefazolin plus metronidazole versus existing multi-dose regimen for prophylaxis in caesarean section
por: Pore, Shraddha M., et al.
Publicado: (2012)

Randomized controlled trial of cefazolin monotherapy versus cefazolin plus azithromycin single dose prophylaxis for cesarean deliveries: A developing country's perspective
por: Jyothi, Manjeera S., et al.
Publicado: (2019)

1465. Two- versus Three-Gram Cefazolin Dosing for Surgical Prophylaxis in Colorectal Surgery Procedures
por: Collins, Curtis D, et al.
Publicado: (2023)

Peri-operative pharmacokinetics of cefazolin prophylaxis during valve replacement surgery
por: Alli, Ahmad, et al.
Publicado: (2023)

Intraosseous concentration and inhibitory effect of different intravenous cefazolin doses used in preoperative prophylaxis of total knee arthroplasty
por: Angthong, Chayanin, et al.
Publicado: (2015)

Prophylactic Cefazolin Dosing in Obesity—a Systematic Review
por: Coates, Matthew, et al.
Publicado: (2022)

Cefazolin and an aminoglycoside compared with cefazolin alone for the antimicrobial prophylaxis of type III open orthopedic fractures
por: Depcinski, Shawn C., et al.
Publicado: (2019)

Prophylactic Cefazolin Dosing and Surgical Site Infections: Does the Dose Matter in Obese Patients?
por: Hussain, Zahid, et al.
Publicado: (2018)

1562. Safety and Efficacy of High-Dose Cefazolin Therapy in Obesity
por: Simpson, Timothy, et al.
Publicado: (2019)

Incidence of postpartum endomyometritis following single-dose antibiotic prophylaxis with either ampicillin/sulbactam, cefazolin, or cefotetan in high-risk cesarean section patients.
por: Noyes, N, et al.
Publicado: (1998)

Increasing cefazolin use for surgical prophylaxis in penicillin-allergy–labeled patients
por: VanderVelde, Kathryn A., et al.
Publicado: (2023)

Rational dosage regimens for cephalothin and cefazolin using pharmacokinetics and pharmacodynamics analysis in healthy horses
por: Kuroda, Taisuke, et al.
Publicado: (2021)

Challenges in Antifungal Therapy in Diabetes Mellitus
por: Mohd Sazlly Lim, Sazlyna, et al.
Publicado: (2020)

Single Dose Versus 72-Hour Course of Ceftriazone for Antibiotic Prophylaxis in Preventing Post-Caesarean Wound Infection: A Randomized Control Trial
por: Zubairu, Usman Danjuma, et al.
Publicado: (2023)

A Population Pharmacokinetic Model-Guided Evaluation of Ceftolozane-Tazobactam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration
por: Sime, Fekade B., et al.
Publicado: (2019)

Pharmacodynamics of Aerosolized Fosfomycin and Amikacin against Resistant Clinical Isolates of Pseudomonas aeruginosa and Klebsiella pneumoniae in a Hollow-Fiber Infection Model: Experimental Basis for Combination Therapy
por: Sime, Fekade Bruck, et al.
Publicado: (2016)

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?
por: Wong, Gloria, et al.
Publicado: (2014)

Results at seven years after the use of intracamerular cefazolin as an endophthalmitis prophylaxis in cataract surgery
por: Romero-Aroca, Pedro, et al.
Publicado: (2012)

Outcome of preoperative cefazolin use for infection prophylaxis in patients with self-reported penicillin allergy
por: Michaud, Laura, et al.
Publicado: (2023)

Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone
por: Sathyan, Gayatri, et al.
Publicado: (2007)

A 24 hour naproxen dose on gastrointestinal distress and performance during cycling in the heat
por: Emerson, Dawn M., et al.
Publicado: (2020)

Safety and Effectiveness of High-Dose Cefazolin in Patients With High Body Weight: A Retrospective Cohort Study
por: Ryu, HaYoung, et al.
Publicado: (2022)

HOW RELIABLE IS 24 HOUR SERUM LITHIUM LEVEL AFTER A TEST DOSE OF LITHIUM IN PREDICTING OPTIMAL LITHIUM DOSE?
por: Kuruvilla, K., et al.
Publicado: (1989)

Antimicrobial Prophylaxis in Instrumented Spinal Fusion Surgery: A Comparative Analysis of 24-Hour and 72-Hour Dosages
por: Marimuthu, Chandrasekaran, et al.
Publicado: (2016)

Pharmacodynamic Modeling of the Entire Time Course of Leukopenia after a 3‐Hour Infusion of Paclitaxel
por: Minami, Hironobu, et al.
Publicado: (2001)

Pharmacokinetic and Pharmacodynamic Considerations in Antimalarial Dose Optimization
por: White, Nicholas J.
Publicado: (2013)

Pharmacodynamics of natalizumab extended interval dosing in MS
por: Zhovtis Ryerson, Lana, et al.
Publicado: (2020)

Repeated-Dose Pharmacodynamics of Pimobendan in Healthy Cats
por: Sugimoto, Keisuke, et al.
Publicado: (2022)

Pharmacodynamic evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum β-lactamase-producing and non-producing Escherichia coli clinical isolates in a hollow-fibre infection model
por: Islam, Kamrul, et al.
Publicado: (2022)

Does Beta-lactam Pharmacokinetic Variability in Critically Ill Patients Justify Therapeutic Drug Monitoring? A Systematic Review
por: Sime, Fekade Bruck, et al.
Publicado: (2012)

Dalbavancin, Vancomycin and Daptomycin Alone and in Combination with Cefazolin against Resistant Phenotypes of Staphylococcus aureus in a Pharmacokinetic/Pharmacodynamic Model
por: Abdul-Mutakabbir, Jacinda C., et al.
Publicado: (2020)

Effect of Cefazolin Prophylaxis on Postoperative Infectious Complications in Elective Laparoscopic Cholecystectomy: A Prospective Randomized Study
por: Turk, Emin, et al.
Publicado: (2013)

1094. Safety of Administering Cefazolin vs. Other Antibiotics in Penicillin Allergic Patients with Anaphylaxis for Surgical Prophylaxis
por: Song, Wendy, et al.
Publicado: (2019)

Acute Multi-Organ Toxicity During 24-Hour Dosing of Intravenous Amiodarone: A Case Report
por: Liwag, Terrin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5nnup7rb15s8foeuvm74q5dfc1