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Macronutrient Intake in Pregnancy and Child Cognitive and Behavioural Outcomes
Prenatal nutrient exposures can impact on brain development and disease susceptibility across the lifespan. It is well established that maternal macronutrient intake during pregnancy influences foetal and infant development. Therefore, we hypothesise that macronutrient intakes during pregnancy are c...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161020/ https://www.ncbi.nlm.nih.gov/pubmed/34065501 http://dx.doi.org/10.3390/children8050425 |
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author | Taylor, Rachael M. Blumfield, Michelle L. Ashton, Lee M. Hure, Alexis J. Smith, Roger Buckley, Nick Drysdale, Karen Collins, Clare E. |
author_facet | Taylor, Rachael M. Blumfield, Michelle L. Ashton, Lee M. Hure, Alexis J. Smith, Roger Buckley, Nick Drysdale, Karen Collins, Clare E. |
author_sort | Taylor, Rachael M. |
collection | PubMed |
description | Prenatal nutrient exposures can impact on brain development and disease susceptibility across the lifespan. It is well established that maternal macronutrient intake during pregnancy influences foetal and infant development. Therefore, we hypothesise that macronutrient intakes during pregnancy are correlated with cognitive development during early childhood. The current study aimed to investigate the relationship between maternal macronutrient intake during pregnancy and child cognitive and behavioural outcomes at age 4 years. We analysed prospective data from a cohort of 64 Australian mother–child dyads. Maternal macronutrient intake was assessed using a validated 74-item food frequency questionnaire at 2 timepoints during pregnancy. Child cognition and behaviour were measured at age 4 years using the validated Wechsler Preschool and Primary Scale of Intelligence, 3rd version (WPPSI-III) and the Child Behaviour Checklist (CBC). Linear regression models were used to quantify statistical relationships and were adjusted for maternal age, education, pre-pregnancy BMI, breastfeeding duration and birthweight. Child Performance IQ was inversely associated with maternal starch intake (b = −11.02, p = 0.03). However, no other associations were found. Further research is needed to explore the association between different types of starch consumed during pregnancy and child cognitive development. |
format | Online Article Text |
id | pubmed-8161020 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-81610202021-05-29 Macronutrient Intake in Pregnancy and Child Cognitive and Behavioural Outcomes Taylor, Rachael M. Blumfield, Michelle L. Ashton, Lee M. Hure, Alexis J. Smith, Roger Buckley, Nick Drysdale, Karen Collins, Clare E. Children (Basel) Article Prenatal nutrient exposures can impact on brain development and disease susceptibility across the lifespan. It is well established that maternal macronutrient intake during pregnancy influences foetal and infant development. Therefore, we hypothesise that macronutrient intakes during pregnancy are correlated with cognitive development during early childhood. The current study aimed to investigate the relationship between maternal macronutrient intake during pregnancy and child cognitive and behavioural outcomes at age 4 years. We analysed prospective data from a cohort of 64 Australian mother–child dyads. Maternal macronutrient intake was assessed using a validated 74-item food frequency questionnaire at 2 timepoints during pregnancy. Child cognition and behaviour were measured at age 4 years using the validated Wechsler Preschool and Primary Scale of Intelligence, 3rd version (WPPSI-III) and the Child Behaviour Checklist (CBC). Linear regression models were used to quantify statistical relationships and were adjusted for maternal age, education, pre-pregnancy BMI, breastfeeding duration and birthweight. Child Performance IQ was inversely associated with maternal starch intake (b = −11.02, p = 0.03). However, no other associations were found. Further research is needed to explore the association between different types of starch consumed during pregnancy and child cognitive development. MDPI 2021-05-20 /pmc/articles/PMC8161020/ /pubmed/34065501 http://dx.doi.org/10.3390/children8050425 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Taylor, Rachael M. Blumfield, Michelle L. Ashton, Lee M. Hure, Alexis J. Smith, Roger Buckley, Nick Drysdale, Karen Collins, Clare E. Macronutrient Intake in Pregnancy and Child Cognitive and Behavioural Outcomes |
title | Macronutrient Intake in Pregnancy and Child Cognitive and Behavioural Outcomes |
title_full | Macronutrient Intake in Pregnancy and Child Cognitive and Behavioural Outcomes |
title_fullStr | Macronutrient Intake in Pregnancy and Child Cognitive and Behavioural Outcomes |
title_full_unstemmed | Macronutrient Intake in Pregnancy and Child Cognitive and Behavioural Outcomes |
title_short | Macronutrient Intake in Pregnancy and Child Cognitive and Behavioural Outcomes |
title_sort | macronutrient intake in pregnancy and child cognitive and behavioural outcomes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161020/ https://www.ncbi.nlm.nih.gov/pubmed/34065501 http://dx.doi.org/10.3390/children8050425 |
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