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RABL6A Regulates Schwann Cell Senescence in an RB1-Dependent Manner
Schwann cells are normally quiescent, myelinating glia cells of the peripheral nervous system. Their aberrant proliferation and transformation underlie the development of benign tumors (neurofibromas) as well as deadly malignant peripheral nerve sheath tumors (MPNSTs). We discovered a new driver of...
Autores principales: | Kohlmeyer, Jordan L., Kaemmer, Courtney A., Umesalma, Shaikamjad, Gourronc, Francoise A., Klingelhutz, Aloysius J., Quelle, Dawn E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161079/ https://www.ncbi.nlm.nih.gov/pubmed/34065204 http://dx.doi.org/10.3390/ijms22105367 |
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