Cargando…

The Interaction between Reactive Peritoneal Mesothelial Cells and Tumor Cells via Extracellular Vesicles Facilitates Colorectal Cancer Dissemination

SIMPLE SUMMARY: Emerging evidence has suggested that cancer-derived extracellular vesicles (EVs) have a crucial role in mediating directional metastasis to the peritoneal surface in colorectal cancer (CRC). We investigated the EV-mediated crosstalk between tumor and mesothelial cells which may drive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Serratì, Simona, Porcelli, Letizia, Fragassi, Francesco, Garofoli, Marianna, Di Fonte, Roberta, Fucci, Livia, Iacobazzi, Rosa Maria, Palazzo, Antonio, Margheri, Francesca, Cristiani, Grazia, Albano, Anna, De Luca, Raffaele, Altomare, Donato Francesco, Simone, Michele, Azzariti, Amalia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161093/ https://www.ncbi.nlm.nih.gov/pubmed/34065529 http://dx.doi.org/10.3390/cancers13102505

Ejemplares similares

The β-adrenergic receptor antagonist propranolol offsets resistance mechanisms to chemotherapeutics in diverse sarcoma subtypes: a pilot study
por: Porcelli, Letizia, et al.
Publicado: (2020)

CAFs and TGF-β Signaling Activation by Mast Cells Contribute to Resistance to Gemcitabine/Nabpaclitaxel in Pancreatic Cancer
por: Porcelli, Letizia, et al.
Publicado: (2019)

uPAR(+) extracellular vesicles: a robust biomarker of resistance to checkpoint inhibitor immunotherapy in metastatic melanoma patients
por: Porcelli, Letizia, et al.
Publicado: (2021)

Circulating extracellular vesicles expressing PD1 and PD-L1 predict response and mediate resistance to checkpoint inhibitors immunotherapy in metastatic melanoma
por: Serratì, Simona, et al.
Publicado: (2022)

Microfluidic-Assisted Preparation of Targeted pH-Responsive Polymeric Micelles Improves Gemcitabine Effectiveness in PDAC: In Vitro Insights
por: Iacobazzi, Rosa Maria, et al.
Publicado: (2021)

Hydroxy-Propil-β-Cyclodextrin Inclusion Complexes of two Biphenylnicotinamide Derivatives: Formulation and Anti-Proliferative Activity Evaluation in Pancreatic Cancer Cell Models
por: Iacobazzi, Rosa Maria, et al.
Publicado: (2020)

Cervical cancer benefits from trabectedin combination with the β-blocker propranolol: in vitro and ex vivo evaluations in patient-derived organoids
por: Di Fonte, Roberta, et al.
Publicado: (2023)

Circulating extracellular vesicles are monitoring biomarkers of anti-PD1 response and enhancer of tumor progression and immunosuppression in metastatic melanoma
por: Serratì, Simona, et al.
Publicado: (2023)

The ERRα–VDR axis promotes calcitriol degradation and estrogen signaling in breast cancer cells, while VDR‐CYP24A1‐ERRα overexpression correlates with poor prognosis in patients with basal‐like breast cancer
por: Danza, Katia, et al.
Publicado: (2021)

The Role of Non-Coding RNAs as Prognostic Factor, Predictor of Drug Response or Resistance and Pharmacological Targets, in the Cutaneous Squamous Cell Carcinoma
por: Garofoli, Marianna, et al.
Publicado: (2020)

Plasma-activated medium triggers cell death and the presentation of immune activating danger signals in melanoma and pancreatic cancer cells
por: Azzariti, Amalia, et al.
Publicado: (2019)

Long Non-Coding RNA Landscape in Prostate Cancer Molecular Subtypes: A Feature Selection Approach
por: De Summa, Simona, et al.
Publicado: (2021)

Synthesis, Characterization, and Cytotoxicity of the First Oxaliplatin Pt(IV) Derivative Having a TSPO Ligand in the Axial Position
por: Savino, Salvatore, et al.
Publicado: (2016)

Tomatine Displays Antitumor Potential in In Vitro Models of Metastatic Melanoma
por: Serratì, Simona, et al.
Publicado: (2020)

Gene Expression Comparison between the Lymph Node-Positive and -Negative Reveals a Peculiar Immune Microenvironment Signature and a Theranostic Role for WNT Targeting in Pancreatic Ductal Adenocarcinoma: A Pilot Study
por: Argentiero, Antonella, et al.
Publicado: (2019)

SPHK1‐induced autophagy in peritoneal mesothelial cell enhances gastric cancer peritoneal dissemination
por: Yin, Songcheng, et al.
Publicado: (2019)

Potential predictive role of chemotherapy-induced changes of soluble CD40 ligand in untreated advanced pancreatic ductal adenocarcinoma
por: Azzariti, Amalia, et al.
Publicado: (2016)

Mechanisms of Peritoneal Mesothelial Cells in Peritoneal Adhesion
por: Wang, Ruipeng, et al.
Publicado: (2022)

Grape seed extracts modify the outcome of oxaliplatin in colon cancer cells by interfering with cellular mechanisms of drug cytotoxicity
por: Porcelli, Letizia, et al.
Publicado: (2017)

Ovarian Cancer-Associated Mesothelial Cells: Transdifferentiation to Minions of Cancer and Orchestrate Developing Peritoneal Dissemination
por: Mogi, Kazumasa, et al.
Publicado: (2021)

Adrenomedullin in peritoneal effluent expressed by peritoneal mesothelial cells
por: Kono, Rika, et al.
Publicado: (2013)

Role of Peritoneal Mesothelial Cells in the Progression of Peritoneal Metastases
por: Li, Junliang, et al.
Publicado: (2022)

High Adhesion of Tumor Cells to Mesothelial Monolayers Derived from Peritoneal Wash of Disseminated Gastrointestinal Cancers
por: Ranieri, Danilo, et al.
Publicado: (2013)

Trehalose ameliorates peritoneal fibrosis by promoting Snail degradation and inhibiting mesothelial-to-mesenchymal transition in mesothelial cells
por: Miyake, Taito, et al.
Publicado: (2020)

Current Landscape and Future Direction of PD-1/PD-L1 Checkpoint Inhibitors in Cancer Treatment
por: Serratì, Simona, et al.
Publicado: (2023)

The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis
por: Rynne-Vidal, Angela, et al.
Publicado: (2015)

MiR-29b may suppresses peritoneal metastases through inhibition of the mesothelial–mesenchymal transition (MMT) of human peritoneal mesothelial cells
por: Kimura, Yuki, et al.
Publicado: (2022)

Barasertib: a novel approach for the treatment of metastatic melanoma
por: Azzariti, Amalia, et al.
Publicado: (2014)

Mechanisms of Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells During Peritoneal Dialysis
por: Lee, Hi Bahl, et al.
Publicado: (2007)

The Effect of Statin on Epithelial-Mesenchymal Transition in Peritoneal Mesothelial Cells
por: Chang, Tae Ik, et al.
Publicado: (2014)

Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells
por: Kang, Seok Hui, et al.
Publicado: (2019)

Mesothelial-to-Mesenchymal Transition and Exosomes in Peritoneal Metastasis of Ovarian Cancer
por: Pascual-Antón, Lucía, et al.
Publicado: (2021)

Pathophysiological Changes to the Peritoneal Membrane during PD-Related Peritonitis: The Role of Mesothelial Cells
por: Yung, Susan, et al.
Publicado: (2012)

Tamoxifen Ameliorates Peritoneal Membrane Damage by Blocking Mesothelial to Mesenchymal Transition in Peritoneal Dialysis
por: Loureiro, Jesús, et al.
Publicado: (2013)

Loosening of the mesothelial barrier as an early therapeutic target to preserve peritoneal function in peritoneal dialysis
por: Kang, Duk-Hee
Publicado: (2020)

Expression of XBP1s in peritoneal mesothelial cells is critical for inflammation-induced peritoneal fibrosis
por: Liu, An, et al.
Publicado: (2019)

Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy
por: Porcelli, Letizia, et al.
Publicado: (2015)

Salting-Out Approach Is Worthy of Comparison with Ultracentrifugation for Extracellular Vesicle Isolation from Tumor and Healthy Models
por: Serratì, Simona, et al.
Publicado: (2021)

Production of IL1-beta by ovarian cancer cells induces mesothelial cell beta1-integrin expression facilitating peritoneal dissemination
por: Watanabe, Takafumi, et al.
Publicado: (2012)

Behind the Scene: Exploiting MC1R in Skin Cancer Risk and Prevention
por: Manganelli, Michele, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_10jtqn7hfbpn6a57u6ohga5gud