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The Perfect Condition for the Rising of Superbugs: Person-to-Person Contact and Antibiotic Use Are the Key Factors Responsible for the Positive Correlation between Antibiotic Resistance Gene Diversity and Virulence Gene Diversity in Human Metagenomes

Human metagenomes with a high diversity of virulence genes tend to have a high diversity of antibiotic-resistance genes and vice-versa. To understand this positive correlation, we simulated the transfer of these genes and bacterial pathogens in a community of interacting people that take antibiotics...

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Detalles Bibliográficos
Autores principales: Domingues, Célia P. F., Rebelo, João S., Pothier, Joël, Monteiro, Francisca, Nogueira, Teresa, Dionisio, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161104/
https://www.ncbi.nlm.nih.gov/pubmed/34065307
http://dx.doi.org/10.3390/antibiotics10050605