Cargando…

The Perfect Condition for the Rising of Superbugs: Person-to-Person Contact and Antibiotic Use Are the Key Factors Responsible for the Positive Correlation between Antibiotic Resistance Gene Diversity and Virulence Gene Diversity in Human Metagenomes

Human metagenomes with a high diversity of virulence genes tend to have a high diversity of antibiotic-resistance genes and vice-versa. To understand this positive correlation, we simulated the transfer of these genes and bacterial pathogens in a community of interacting people that take antibiotics...

Descripción completa

Detalles Bibliográficos
Autores principales:	Domingues, Célia P. F., Rebelo, João S., Pothier, Joël, Monteiro, Francisca, Nogueira, Teresa, Dionisio, Francisco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161104/ https://www.ncbi.nlm.nih.gov/pubmed/34065307 http://dx.doi.org/10.3390/antibiotics10050605

Ejemplares similares

Antibiotic Resistance Gene Diversity and Virulence Gene Diversity Are Correlated in Human Gut and Environmental Microbiomes
por: Escudeiro, Pedro, et al.
Publicado: (2019)

Are Virulence and Antibiotic Resistance Genes Linked? A Comprehensive Analysis of Bacterial Chromosomes and Plasmids
por: Darmancier, Helena, et al.
Publicado: (2022)

COVID-19 Lockdowns May Reduce Resistance Genes Diversity in the Human Microbiome and the Need for Antibiotics
por: Rebelo, João S., et al.
Publicado: (2021)

The Impact of Non-Pathogenic Bacteria on the Spread of Virulence and Resistance Genes
por: Dionisio, Francisco, et al.
Publicado: (2023)

Functional Metagenomics Reveals Previously Unrecognized Diversity of Antibiotic Resistance Genes in Gulls
por: Martiny, Adam C., et al.
Publicado: (2011)

Mining metagenomes reveals diverse antibiotic biosynthetic genes in uncultured microbial communities
por: Amin, Dina H., et al.
Publicado: (2023)

Bacterial persistence is essential for susceptible cell survival in indirect resistance, mainly for lower cell densities
por: Rebelo, João S., et al.
Publicado: (2021)

Metagenomic strategies identify diverse integron‐integrase and antibiotic resistance genes in the Antarctic environment
por: Antelo, Verónica, et al.
Publicado: (2021)

Daunorubicin resensitizes Gram-negative superbugs to the last-line antibiotics and prevents the transmission of antibiotic resistance
por: Cai, Jinju, et al.
Publicado: (2023)

Antibiotic Resistant Superbugs: Assessment of the Interrelationship of Occurrence in Clinical Settings and Environmental Niches
por: Adegoke, Anthony Ayodeji, et al.
Publicado: (2016)

Phages against killer superbugs: An enticing strategy against antibiotics-resistant pathogens
por: Baral, Bikash
Publicado: (2023)

Metagenomics Reveals the Diversity and Taxonomy of Carbohydrate-Active Enzymes and Antibiotic Resistance Genes in Suancai Bacterial Communities
por: Song, Qiaozhi, et al.
Publicado: (2022)

Superbug vs. Superphage A Review of The Perfect Predator and an Interview with Dr. Chip Schooley
por: Panosian Dunavan, Claire
Publicado: (2020)

Metagenomic Survey Reveals More Diverse and Abundant Antibiotic Resistance Genes in Municipal Wastewater Than Hospital Wastewater
por: Zhang, Dengwei, et al.
Publicado: (2021)

Diverse Antibiotic Resistance Genes in Dairy Cow Manure
por: Wichmann, Fabienne, et al.
Publicado: (2014)

Shared antibiotic resistance and virulence genes in Staphylococcus aureus from diverse animal hosts
por: Bruce, Spencer A., et al.
Publicado: (2022)

The other superbugs
por: Fleming, Nic
Publicado: (2021)

Bacterial diversity and prevalence of antibiotic resistance genes in the oral microbiome
por: Almeida, Viviane de Sousa Moreira, et al.
Publicado: (2020)

Plasmids Increase the Competitive Ability of Plasmid-Bearing Cells Even When Transconjugants Are Poor Donors, as Shown by Computer Simulations
por: Rebelo, João S., et al.
Publicado: (2023)

Multi-Drug Resistance in Bacterial Genomes—A Comprehensive Bioinformatic Analysis
por: Domingues, Célia P. F., et al.
Publicado: (2023)

Toward Antibiotic Stewardship: Route of Antibiotic Administration Impacts the Microbiota and Resistance Gene Diversity in Swine Feces
por: Ricker, Nicole, et al.
Publicado: (2020)

Editorial: Emerging multidrug-resistant bacterial pathogens “superbugs”: A rising public health threat
por: Algammal, Abdelazeem, et al.
Publicado: (2023)

Pediatric Fecal Microbiota Harbor Diverse and Novel Antibiotic Resistance Genes
por: Moore, Aimée M., et al.
Publicado: (2013)

Cyanobacterial blooms contribute to the diversity of antibiotic-resistance genes in aquatic ecosystems
por: Zhang, Qi, et al.
Publicado: (2020)

BacARscan: an in silico resource to discern diversity in antibiotic resistance genes
por: Pandey, Deeksha, et al.
Publicado: (2022)

Diversity of antibiotic resistance genes in soils with four different fertilization treatments
por: Wang, Zhuoran, et al.
Publicado: (2023)

Identification and reconstruction of novel antibiotic resistance genes from metagenomes
por: Berglund, Fanny, et al.
Publicado: (2019)

Geographic pattern of antibiotic resistance genes in the metagenomes of the giant panda
por: Hu, Ting, et al.
Publicado: (2020)

Pro-Diversity Beliefs and the Diverse Person’s Burden
por: Steel, Daniel, et al.
Publicado: (2022)

The Social Distancing Imposed To Contain COVID-19 Can Affect Our Microbiome: a Double-Edged Sword in Human Health
por: Domingues, Célia P. F., et al.
Publicado: (2020)

A metagenomic analysis for combination therapy of multiple classes of antibiotics on the prevention of the spread of antibiotic-resistant genes
por: Igo, Matthew, et al.
Publicado: (2023)

Quantitative PCR versus metagenomics for monitoring antibiotic resistance genes: balancing high sensitivity and broad coverage
por: Ferreira, Catarina, et al.
Publicado: (2023)

Sorting out the Superbugs: Potential of Sortase A Inhibitors among Other Antimicrobial Strategies to Tackle the Problem of Antibiotic Resistance
por: Zrelovs, Nikita, et al.
Publicado: (2021)

From Hospital to Community: Exploring Antibiotic Resistance and Genes Associated with Virulence Factor Diversity of Coagulase-Positive Staphylococci
por: Aqel, Hazem, et al.
Publicado: (2023)

Launching the Antibiotic Era: Personal Accounts of the Discovery and Use of the First Antibiotics
por: Bia, Frank J.
Publicado: (1991)

Launching the antibiotic era: personal accounts of the discovery and use of the first antibiotics
por: Weatherall, M.
Publicado: (1991)

The diversity of uncharacterized antibiotic resistance genes can be predicted from known gene variants—but not always
por: Bengtsson-Palme, Johan
Publicado: (2018)

Diversity of bacterial lactase genes in intestinal contents of mice with antibiotics-induced diarrhea
por: Long, Cheng-Xing, et al.
Publicado: (2017)

Effects of Pyroligneous Acid on Diversity and Dynamics of Antibiotic Resistance Genes in Alfalfa Silage
por: Zhang, Qing, et al.
Publicado: (2022)

Estuarine Aquacultures at the Crossroads of Animal Production and Antibacterial Resistance: A Metagenomic Approach to the Resistome
por: Silva, Daniel G., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jav67ncia9q9jk3oq302egnhtl