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Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents

SIMPLE SUMMARY: The gene-regulatory factors ATF5, CEBPB and CEBPD promote survival, growth, metastasis and treatment resistance of a range of cancer cell types. Presently, no drugs target all three at once. Here, with the aim of treating cancers, we designed novel cell-penetrating peptides that inte...

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Detalles Bibliográficos
Autores principales: Zhou, Qing, Sun, Xiotian, Pasquier, Nicolas, Jefferson, Parvaneh, Nguyen, Trang T. T., Siegelin, Markus D., Angelastro, James M., Greene, Lloyd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161188/
https://www.ncbi.nlm.nih.gov/pubmed/34065488
http://dx.doi.org/10.3390/cancers13102504