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Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents
SIMPLE SUMMARY: The gene-regulatory factors ATF5, CEBPB and CEBPD promote survival, growth, metastasis and treatment resistance of a range of cancer cell types. Presently, no drugs target all three at once. Here, with the aim of treating cancers, we designed novel cell-penetrating peptides that inte...
Autores principales: | Zhou, Qing, Sun, Xiotian, Pasquier, Nicolas, Jefferson, Parvaneh, Nguyen, Trang T. T., Siegelin, Markus D., Angelastro, James M., Greene, Lloyd A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161188/ https://www.ncbi.nlm.nih.gov/pubmed/34065488 http://dx.doi.org/10.3390/cancers13102504 |
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