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Iron-Bound Lipocalin-2 Protects Renal Cell Carcinoma from Ferroptosis

While the importance of the iron-load of lipocalin-2 (Lcn-2) in promoting tumor progression is widely appreciated, underlying molecular mechanisms largely remain elusive. Considering its role as an iron-transporter, we aimed at clarifying iron-loaded, holo-Lcn-2 (hLcn-2)-dependent signaling pathways...

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Detalles Bibliográficos
Autores principales: Meier, Julia K., Schnetz, Matthias, Beck, Susanne, Schmid, Tobias, Dominguez, Monica, Kalinovic, Sanela, Daiber, Andreas, Brüne, Bernhard, Jung, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161288/
https://www.ncbi.nlm.nih.gov/pubmed/34069743
http://dx.doi.org/10.3390/metabo11050329

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