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Bone Mineral Density and Hemoglobin Levels: Opposite Associations in Younger and Older Women

This cross-sectional, retrospective medical record review study aimed to investigate the association between hemoglobin levels and bone mineral density (BMD) in adult women. Medical records obtained from general health examinations conducted from June 2014 to July 2020 at a regional hospital in sout...

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Detalles Bibliográficos
Autores principales: Chuang, Tzyy-Ling, Koo, Malcolm, Chuang, Mei-Hua, Wang, Yuh-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161311/
https://www.ncbi.nlm.nih.gov/pubmed/34065536
http://dx.doi.org/10.3390/ijerph18105495
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author Chuang, Tzyy-Ling
Koo, Malcolm
Chuang, Mei-Hua
Wang, Yuh-Feng
author_facet Chuang, Tzyy-Ling
Koo, Malcolm
Chuang, Mei-Hua
Wang, Yuh-Feng
author_sort Chuang, Tzyy-Ling
collection PubMed
description This cross-sectional, retrospective medical record review study aimed to investigate the association between hemoglobin levels and bone mineral density (BMD) in adult women. Medical records obtained from general health examinations conducted from June 2014 to July 2020 at a regional hospital in southern Taiwan were reviewed. Anthropometric and laboratory data were recorded. BMD of the lumbar spine and bilateral femoral neck regions was assessed by dual energy X-ray absorptiometry. Linear regression analysis was used to assess the association between BMD and hemoglobin level with and without adjusting for other anthropometric and laboratory data. The study included 9606 female patients with a mean age of 55.9 years. Of these, 2756 (28.7%) were aged ≤ 50 years and 6850 (71.3%) were aged > 50 years. Results from multiple linear regression analysis showed that hemoglobin and femoral and lumbar spine BMD were significantly correlated. A higher hemoglobin level was significantly associated with a lower BMD level in females aged ≤ 50 years, but with a higher BMD level in those aged > 50 years. Given the relationship between bone metabolism and hematopoiesis, additional research is needed to elucidate the association between hemoglobin and BMD levels in different age groups, particularly in premenopausal and perimenopausal women.
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spelling pubmed-81613112021-05-29 Bone Mineral Density and Hemoglobin Levels: Opposite Associations in Younger and Older Women Chuang, Tzyy-Ling Koo, Malcolm Chuang, Mei-Hua Wang, Yuh-Feng Int J Environ Res Public Health Article This cross-sectional, retrospective medical record review study aimed to investigate the association between hemoglobin levels and bone mineral density (BMD) in adult women. Medical records obtained from general health examinations conducted from June 2014 to July 2020 at a regional hospital in southern Taiwan were reviewed. Anthropometric and laboratory data were recorded. BMD of the lumbar spine and bilateral femoral neck regions was assessed by dual energy X-ray absorptiometry. Linear regression analysis was used to assess the association between BMD and hemoglobin level with and without adjusting for other anthropometric and laboratory data. The study included 9606 female patients with a mean age of 55.9 years. Of these, 2756 (28.7%) were aged ≤ 50 years and 6850 (71.3%) were aged > 50 years. Results from multiple linear regression analysis showed that hemoglobin and femoral and lumbar spine BMD were significantly correlated. A higher hemoglobin level was significantly associated with a lower BMD level in females aged ≤ 50 years, but with a higher BMD level in those aged > 50 years. Given the relationship between bone metabolism and hematopoiesis, additional research is needed to elucidate the association between hemoglobin and BMD levels in different age groups, particularly in premenopausal and perimenopausal women. MDPI 2021-05-20 /pmc/articles/PMC8161311/ /pubmed/34065536 http://dx.doi.org/10.3390/ijerph18105495 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chuang, Tzyy-Ling
Koo, Malcolm
Chuang, Mei-Hua
Wang, Yuh-Feng
Bone Mineral Density and Hemoglobin Levels: Opposite Associations in Younger and Older Women
title Bone Mineral Density and Hemoglobin Levels: Opposite Associations in Younger and Older Women
title_full Bone Mineral Density and Hemoglobin Levels: Opposite Associations in Younger and Older Women
title_fullStr Bone Mineral Density and Hemoglobin Levels: Opposite Associations in Younger and Older Women
title_full_unstemmed Bone Mineral Density and Hemoglobin Levels: Opposite Associations in Younger and Older Women
title_short Bone Mineral Density and Hemoglobin Levels: Opposite Associations in Younger and Older Women
title_sort bone mineral density and hemoglobin levels: opposite associations in younger and older women
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161311/
https://www.ncbi.nlm.nih.gov/pubmed/34065536
http://dx.doi.org/10.3390/ijerph18105495
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