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Gut Organoid as a New Platform to Study Alginate and Chitosan Mediated PLGA Nanoparticles for Drug Delivery
Intestinal organoids can be used as an ex vivo epithelial model to study different drug delivery effects on epithelial cells’ luminal surface. In this study, the impact of surface charge on the delivery of 5-ASA loaded PLGA nanoparticles into the lumen of organoids was investigated. Alginate and chi...
Autores principales: | Davoudi, Zahra, Peroutka-Bigus, Nathan, Bellaire, Bryan, Jergens, Albert, Wannemuehler, Michael, Wang, Qun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161322/ https://www.ncbi.nlm.nih.gov/pubmed/34065505 http://dx.doi.org/10.3390/md19050282 |
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