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Charge Regulation during Amyloid Formation of α-Synuclein

[Image: see text] Electrostatic interactions play crucial roles in protein function. Measuring pK(a) value perturbations upon complex formation or self-assembly of e.g. amyloid fibrils gives valuable information about the effect of electrostatic interactions in those processes. Site-specific pK(a) v...

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Detalles Bibliográficos
Autores principales: Pálmadóttir, Tinna, Malmendal, Anders, Leiding, Thom, Lund, Mikael, Linse, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161422/
https://www.ncbi.nlm.nih.gov/pubmed/33998793
http://dx.doi.org/10.1021/jacs.1c01925