SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction

A 26-year-old man with symptomatic SARS-CoV-2 infection developed a sudden-onset acute testicular pain. The echo-doppler images showed massive testicular infarction, so orchiectomy was performed. On gross examination, the surgical specimen showed complete testicular necrosis and diffuse thickening o...

Descripción completa

Detalles Bibliográficos
Autores principales: Parrón, Dámaso, Gartzia, Ane, Iturregui, Ane M., Imaz, Igone, Manini, Claudia, García-Olaverri, Jorge, López, José I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161438/
https://www.ncbi.nlm.nih.gov/pubmed/34066311
http://dx.doi.org/10.3390/clinpract11020037
_version_ 1783700511353995264
author Parrón, Dámaso
Gartzia, Ane
Iturregui, Ane M.
Imaz, Igone
Manini, Claudia
García-Olaverri, Jorge
López, José I.
author_facet Parrón, Dámaso
Gartzia, Ane
Iturregui, Ane M.
Imaz, Igone
Manini, Claudia
García-Olaverri, Jorge
López, José I.
author_sort Parrón, Dámaso
collection PubMed
description A 26-year-old man with symptomatic SARS-CoV-2 infection developed a sudden-onset acute testicular pain. The echo-doppler images showed massive testicular infarction, so orchiectomy was performed. On gross examination, the surgical specimen showed complete testicular necrosis and diffuse thickening of the testicular coverings. Under the microscope, a severe obliterative arteritis was evidenced. SARS-CoV-2 spike antibody was detected by immunohistochemistry in the arterial endothelium. Electron microscopy displayed intracytoplasmic spiky viral particles in endothelial cells. The patient was treated with corticoids and was asymptomatic at last contact.
format Online
Article
Text
id pubmed-8161438
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-81614382021-05-29 SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction Parrón, Dámaso Gartzia, Ane Iturregui, Ane M. Imaz, Igone Manini, Claudia García-Olaverri, Jorge López, José I. Clin Pract Case Report A 26-year-old man with symptomatic SARS-CoV-2 infection developed a sudden-onset acute testicular pain. The echo-doppler images showed massive testicular infarction, so orchiectomy was performed. On gross examination, the surgical specimen showed complete testicular necrosis and diffuse thickening of the testicular coverings. Under the microscope, a severe obliterative arteritis was evidenced. SARS-CoV-2 spike antibody was detected by immunohistochemistry in the arterial endothelium. Electron microscopy displayed intracytoplasmic spiky viral particles in endothelial cells. The patient was treated with corticoids and was asymptomatic at last contact. MDPI 2021-05-06 /pmc/articles/PMC8161438/ /pubmed/34066311 http://dx.doi.org/10.3390/clinpract11020037 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Parrón, Dámaso
Gartzia, Ane
Iturregui, Ane M.
Imaz, Igone
Manini, Claudia
García-Olaverri, Jorge
López, José I.
SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction
title SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction
title_full SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction
title_fullStr SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction
title_full_unstemmed SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction
title_short SARS-CoV-2-Associated Obliterative Arteritis Causing Massive Testicular Infarction
title_sort sars-cov-2-associated obliterative arteritis causing massive testicular infarction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161438/
https://www.ncbi.nlm.nih.gov/pubmed/34066311
http://dx.doi.org/10.3390/clinpract11020037
work_keys_str_mv AT parrondamaso sarscov2associatedobliterativearteritiscausingmassivetesticularinfarction
AT gartziaane sarscov2associatedobliterativearteritiscausingmassivetesticularinfarction
AT iturreguianem sarscov2associatedobliterativearteritiscausingmassivetesticularinfarction
AT imazigone sarscov2associatedobliterativearteritiscausingmassivetesticularinfarction
AT maniniclaudia sarscov2associatedobliterativearteritiscausingmassivetesticularinfarction
AT garciaolaverrijorge sarscov2associatedobliterativearteritiscausingmassivetesticularinfarction
AT lopezjosei sarscov2associatedobliterativearteritiscausingmassivetesticularinfarction

Ejemplares similares