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Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios

As the world continues to suffer from an ever-growing number of confirmed cases of the SARS-CoV-2 novel coronavirus, researchers are at the forefront of developing the best plan to overcome this pandemic through analyzing the pathogenesis, prevention, and treatment options pertaining to the virus. I...

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Autores principales: Tellez, Daniel, Dayal, Sujay, Phan, Phong, Mawley, Ajinkya, Shah, Kush, Consunji, Gabriel, Tellez, Cindy, Ruiz, Kimberly, Sabnis, Rutuja, Dayal, Surbi, Venketaraman, Vishwanath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161456/
https://www.ncbi.nlm.nih.gov/pubmed/34069418
http://dx.doi.org/10.3390/clinpract11020044
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author Tellez, Daniel
Dayal, Sujay
Phan, Phong
Mawley, Ajinkya
Shah, Kush
Consunji, Gabriel
Tellez, Cindy
Ruiz, Kimberly
Sabnis, Rutuja
Dayal, Surbi
Venketaraman, Vishwanath
author_facet Tellez, Daniel
Dayal, Sujay
Phan, Phong
Mawley, Ajinkya
Shah, Kush
Consunji, Gabriel
Tellez, Cindy
Ruiz, Kimberly
Sabnis, Rutuja
Dayal, Surbi
Venketaraman, Vishwanath
author_sort Tellez, Daniel
collection PubMed
description As the world continues to suffer from an ever-growing number of confirmed cases of the SARS-CoV-2 novel coronavirus, researchers are at the forefront of developing the best plan to overcome this pandemic through analyzing the pathogenesis, prevention, and treatment options pertaining to the virus. In the midst of a pandemic, the main route for detection of the virus has been conducting antigen tests for rapid results, using qRT-PCR, and conducting more accurate molecular tests, using rRT-PCR, on samples from patients. Most common treatments for those infected with COVID-19 include Remdesivir, an antiviral, dexamethasone, a steroid, and rarely, monoclonal antibody treatments. Although these treatments exist and are used commonly in hospitals all around the globe, clinicians often challenge the efficacy and benefit of these remedies for the patient. Furthermore, targeted therapies largely focus on interfering with or reducing the binding of viral receptors and host cell receptors affected by the SARS-CoV-2 novel coronavirus. In addition to treatment, the most efficacious method of preventing the spread of COVID-19 is the development of multiple vaccines that have been distributed as well as the development of multiple vaccine candidates that are proving hopeful in preventing severe symptoms of the virus. The exaggerated immune response to the virus proves to be a worrying complication due to widespread inflammation and subsequent clinical sequela. The medical and scientific community as a whole will be expected to respond with the latest in technology and research, and further studies into the pathogenesis, clinical implications, identification, diagnosis, and treatment of COVID-19 will push society past this pandemic.
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spelling pubmed-81614562021-05-29 Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios Tellez, Daniel Dayal, Sujay Phan, Phong Mawley, Ajinkya Shah, Kush Consunji, Gabriel Tellez, Cindy Ruiz, Kimberly Sabnis, Rutuja Dayal, Surbi Venketaraman, Vishwanath Clin Pract Case Report As the world continues to suffer from an ever-growing number of confirmed cases of the SARS-CoV-2 novel coronavirus, researchers are at the forefront of developing the best plan to overcome this pandemic through analyzing the pathogenesis, prevention, and treatment options pertaining to the virus. In the midst of a pandemic, the main route for detection of the virus has been conducting antigen tests for rapid results, using qRT-PCR, and conducting more accurate molecular tests, using rRT-PCR, on samples from patients. Most common treatments for those infected with COVID-19 include Remdesivir, an antiviral, dexamethasone, a steroid, and rarely, monoclonal antibody treatments. Although these treatments exist and are used commonly in hospitals all around the globe, clinicians often challenge the efficacy and benefit of these remedies for the patient. Furthermore, targeted therapies largely focus on interfering with or reducing the binding of viral receptors and host cell receptors affected by the SARS-CoV-2 novel coronavirus. In addition to treatment, the most efficacious method of preventing the spread of COVID-19 is the development of multiple vaccines that have been distributed as well as the development of multiple vaccine candidates that are proving hopeful in preventing severe symptoms of the virus. The exaggerated immune response to the virus proves to be a worrying complication due to widespread inflammation and subsequent clinical sequela. The medical and scientific community as a whole will be expected to respond with the latest in technology and research, and further studies into the pathogenesis, clinical implications, identification, diagnosis, and treatment of COVID-19 will push society past this pandemic. MDPI 2021-05-19 /pmc/articles/PMC8161456/ /pubmed/34069418 http://dx.doi.org/10.3390/clinpract11020044 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Tellez, Daniel
Dayal, Sujay
Phan, Phong
Mawley, Ajinkya
Shah, Kush
Consunji, Gabriel
Tellez, Cindy
Ruiz, Kimberly
Sabnis, Rutuja
Dayal, Surbi
Venketaraman, Vishwanath
Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios
title Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios
title_full Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios
title_fullStr Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios
title_full_unstemmed Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios
title_short Analysis of COVID-19 on Diagnosis, Vaccine, Treatment, and Pathogenesis with Clinical Scenarios
title_sort analysis of covid-19 on diagnosis, vaccine, treatment, and pathogenesis with clinical scenarios
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161456/
https://www.ncbi.nlm.nih.gov/pubmed/34069418
http://dx.doi.org/10.3390/clinpract11020044
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