A Molecular Approach to Quantum Sensing

[Image: see text] The second quantum revolution hinges on the creation of materials that unite atomic structural precision with electronic and structural tunability. A molecular approach to quantum information science (QIS) promises to enable the bottom-up creation of quantum systems. Within the broad reach of QIS, which spans fields ranging from quantum computation to quantum communication, we will focus on quantum sensing. Quantum sensing harnesses quantum control to interrogate the world around us. A broadly applicable class of quantum sensors would feature adaptable environmental compatibility, control over distance from the target analyte, and a tunable energy range of interaction. Molecules enable customizable “designer” quantum sensors with tunable functionality and compatibility across a range of environments. These capabilities offer the potential to bring unmatched sensitivity and spatial resolution to address a wide range of sensing tasks from the characterization of dynamic biological processes to the detection of emergent phenomena in condensed matter. In this Outlook, we outline the concepts and design criteria central to quantum sensors and look toward the next generation of designer quantum sensors based on new classes of molecular sensors.