Cargando…
The Masking Game: Design of Activatable Antibodies and Mimetics for Selective Therapeutics and Cell Control
[Image: see text] The high selectivity and affinity of antibody binding have made antibodies all-pervasive tools in therapy, diagnosis, and basic science. A plethora of chemogenetic approaches has been devised to make antibodies responsive to stimuli ranging from light to enzymatic activity, tempera...
Autores principales: | Lucchi, Roberta, Bentanachs, Jordi, Oller-Salvia, Benjamí |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8161478/ https://www.ncbi.nlm.nih.gov/pubmed/34079893 http://dx.doi.org/10.1021/acscentsci.0c01448 |
Ejemplares similares
-
Protease-Resistant Peptides for Targeting and Intracellular Delivery of Therapeutics
por: Lucana, Maria C., et al.
Publicado: (2021) -
Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
por: Oller-Salvia, Benjamí
Publicado: (2018) -
Chemically Enhanced Peptide and Protein Therapeutics
por: Díaz-Perlas, Cristina, et al.
Publicado: (2023) -
Rapid and Efficient Generation of Stable Antibody–Drug Conjugates via an Encoded Cyclopropene and an Inverse‐Electron‐Demand Diels–Alder Reaction
por: Oller‐Salvia, Benjamí, et al.
Publicado: (2018) -
Efficient Phage Display with Multiple Distinct Non‐Canonical Amino Acids Using Orthogonal Ribosome‐Mediated Genetic Code Expansion
por: Oller‐Salvia, Benjamí, et al.
Publicado: (2019)